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艾滋病患者的肝胆疾病:聚焦于艾滋病胆管病和胆囊疾病。

Hepatobiliary diseases in patients with AIDS: focus on AIDS cholangiopathy and gallbladder disease.

作者信息

Wilcox C M, Mönkemüller K E

机构信息

Division of Gastroenterology and Hepatology,University of Alabama at Birmingham, Ala., USA.

出版信息

Dig Dis. 1998 Jul-Aug;16(4):205-13. doi: 10.1159/000016868.

DOI:10.1159/000016868
PMID:9732180
Abstract

Diseases of the biliary tree and gallbladder are being described with increasing frequency among patients with the acquired immunodeficiency syndrome (AIDS). Despite the profound immunosuppressive therapy transplant recipients receive, these patients do not appear to be affected by these disorders; thus, human immunodeficiency virus (HIV)-infected patients appear to be uniquely susceptible. Most HIV-infected patients that develop cholangiopathy have severe immunodeficiency with CD4 lymphocyte counts <200/mm3. The objective of this review is to summarize the available literature on AIDS-cholangiopathy, focusing on its diagnosis and classification and to suggest an approach for its evaluation and its management.

摘要

在获得性免疫缺陷综合征(AIDS)患者中,胆道系统和胆囊疾病的报道越来越频繁。尽管器官移植受者接受了强效免疫抑制治疗,但这些患者似乎并未受到这些疾病的影响;因此,感染人类免疫缺陷病毒(HIV)的患者似乎特别容易患病。大多数发生胆管病的HIV感染患者存在严重免疫缺陷,CD4淋巴细胞计数<200/mm3。本综述的目的是总结关于艾滋病胆管病的现有文献,重点关注其诊断和分类,并提出一种评估和管理方法。

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