Vardi Y, Siroky M B
J Urol. 1987 Sep;138(3):663-6. doi: 10.1016/s0022-5347(17)43294-0.
We developed a canine model which permits hemodynamic study of the isolated corpus cavernosum. The arterial and venous flow to the corpus cavernosum was measured and pressure was measured in each corpus cavernosum separately. To provide controlled inflow to the corpora, each side was perfused separately with the aorta clamped. It was demonstrated that arterial and nerve supply to the corpus cavernosum is crossed. During unstimulated corporal perfusion, venous outflow from the corpora increased with increased perfusion rate up to a maximum of 40 ml./min. Following pelvic nerve stimulation, intracorporal pressure increased at much lower rates of perfusion. Moreover, it was noted that intracorporal pressure was not transmitted from one side to the other. Thus, in the canine model, each corpus cavernosum may act as a control for the contralateral one. The technique we used to measure venous outflow from the corpora cavernosa, previously undescribed, permits accurate depiction of the hemodynamics of penile erection.
我们开发了一种犬类模型，可用于对离体海绵体进行血流动力学研究。分别测量了海绵体的动脉和静脉血流，并分别测量了每个海绵体的压力。为了控制流入海绵体的血流，在夹闭主动脉的情况下，分别对每一侧进行灌注。结果表明，海绵体的动脉和神经供应是交叉的。在未受刺激的海绵体灌注过程中，随着灌注速率的增加，海绵体的静脉流出量增加，最高可达40毫升/分钟。在盆腔神经刺激后，在低得多的灌注速率下，海绵体内压力升高。此外，还注意到海绵体内压力不会从一侧传递到另一侧。因此，在犬类模型中，每个海绵体都可以作为对侧海绵体的对照。我们用于测量海绵体静脉流出量的技术此前未被描述过，它能够准确描绘阴茎勃起的血流动力学。
