Department of Internal Medicine, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Department of Public Health and Community Programs, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Kathmandu Univ Med J (KUMJ). 2021;19(76):525-527.
The COVID-19 Pneumonia with diabetic ketoacidosis is a dreadful health condition. Diabetic ketoacidosis is one of the severe metabolic complications and it can be precipitated by infection. We presented a case of 48 years female with no known comorbidities who presented with COVID-19 symptoms and with Diabetic Ketoacidosis. The case presented with elevated inflammatory markers, high anion gap metabolic acidosis with type I respiratory failure. During admission, the oxygen saturation had marked drop, later her improvement was steady followed by gradual tapering of the oxygenation. Marked improvement was noticed in the subsequent follow-up. COVID-19 infection can be precipitated by preexisting diabetes or newly diagnosed diabetes and the severity of COVID-19 infection is more pronounced in patients with diabetes mellitus, thus should be managed timely and accordingly. The scarce studies among the COVID-19 cases with diabetic ketoacidosis reflect the need for further studies for the availability of a wider range of information.
伴有糖尿病酮症酸中毒的新冠肺炎肺炎是一种可怕的健康状况。糖尿病酮症酸中毒是一种严重的代谢并发症，可由感染引发。我们报告了一例 48 岁女性病例，该患者无已知合并症，出现了新冠肺炎症状和糖尿病酮症酸中毒。该病例表现为炎症标志物升高、阴离子间隙高代谢性酸中毒伴 I 型呼吸衰竭。住院期间，患者的血氧饱和度明显下降，随后逐渐稳定改善，氧合作用逐渐减少。随后的随访中观察到明显改善。新冠肺炎感染可由先前存在的糖尿病或新诊断的糖尿病引发，且糖尿病患者的新冠肺炎感染更严重，因此应及时进行治疗。糖尿病酮症酸中毒的新冠肺炎病例研究较少，这反映了需要进一步研究以提供更广泛的信息。
