Department of Community Healthcare and Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Eur Geriatr Med. 2022 Dec;13(6):1403-1406. doi: 10.1007/s41999-022-00704-7. Epub 2022 Oct 19.
Frailty is a dynamic status that can worsen or improve. However, changes in their frailty status that occur during hospitalization and their significance have not been comprehensively investigated. In this study, we explored the association between such changes and mortality 3 months after discharge in older adults hospitalized for acute care. In total, 257 participants (mean age 84.95 ± 5.88, 41.6% male) completed comprehensive geriatric assessments, including the Clinical Frailty Scale (CFS) at admission and discharge. Mean CFS score was 5.14 ± 1.35 at admission. CFS scores increased, indicating deteriorating frailty, in 29.2% of the participants (75/257) during hospitalization. Multiple logistic regression analysis demonstrated a positive association between increased CFS score during hospitalization and mortality (odds ratio, 2.987) independent of potential co-founding factors. This deterioration in frailty during hospitalization may be modifiable risk factor of poor prognosis in older adults who need acute care hospitalization.
衰弱是一种动态状态，可以恶化或改善。然而，住院期间衰弱状态的变化及其意义尚未得到全面研究。在这项研究中，我们探讨了在因急性病住院的老年人中，这种变化与出院后 3 个月死亡率之间的关系。共有 257 名参与者（平均年龄 84.95±5.88 岁，41.6%为男性）在入院和出院时完成了全面老年评估，包括临床虚弱量表（CFS）。入院时的平均 CFS 评分为 5.14±1.35。在住院期间，29.2%（75/257）的参与者的 CFS 评分增加，表明虚弱程度恶化。多变量逻辑回归分析表明，住院期间 CFS 评分增加与死亡率呈正相关（比值比，2.987），独立于潜在的混杂因素。这种住院期间的衰弱恶化可能是需要急性病住院治疗的老年人预后不良的可改变的危险因素。
