Xu Chenchu, Wang Yifei, Zhang Dong, Han Longfei, Zhang Yanping, Chen Jie, Li Shuo
IEEE J Biomed Health Inform. 2023 Jan;27(1):87-96. doi: 10.1109/JBHI.2022.3215536. Epub 2023 Jan 4.
Automatic segmentation of myocardial infarction (MI) regions in late gadolinium-enhanced cardiac magnetic resonance images is an essential step in the computed diagnosis of myocardial infarction. Most of the current myocardial infarction region segmentation methods are based on fully supervised deep learning. However, cardiologists' annotation of myocardial infarction regions in cardiac magnetic resonance images during the diagnosis process is time-consuming and expensive. This paper proposes a semi-supervised myocardial infarction segmentation. It consists of two models: 1) a boundary mining model and 2) an adversarial learning model. The boundary mining model can solve the boundary ambiguity problem by enlarging the gap between the foreground and background features, thus segmenting the myocardial infarction region accurately. The adversarial learning model can make the boundary mining model learn from additional unlabeled data by evaluating the segmentation performance and providing pseudo supervision, which significantly increases the robustness of the boundary mining model. We conduct extensive experiments on an in-house myocardial magnetic resonance dataset. The experimental results on six evaluation metrics demonstrate that our method achieves excellent results in myocardial infarction segmentation and outperforms the state-of-the-art semi-supervised methods.
在延迟钆增强心脏磁共振图像中自动分割心肌梗死(MI)区域是心肌梗死计算机诊断的关键步骤。当前大多数心肌梗死区域分割方法基于全监督深度学习。然而,心脏病专家在诊断过程中对心脏磁共振图像中心肌梗死区域进行标注既耗时又昂贵。本文提出一种半监督心肌梗死分割方法。它由两个模型组成:1)边界挖掘模型和2)对抗学习模型。边界挖掘模型可通过扩大前景与背景特征之间的差距来解决边界模糊问题,从而准确分割心肌梗死区域。对抗学习模型能够通过评估分割性能并提供伪监督,使边界挖掘模型从额外的未标记数据中学习,这显著提高了边界挖掘模型的鲁棒性。我们在一个内部心肌磁共振数据集上进行了广泛实验。六个评估指标的实验结果表明,我们的方法在心肌梗死分割方面取得了优异成果,优于当前最先进的半监督方法。