The Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
Psychiatry Res. 2022 Nov;317:114890. doi: 10.1016/j.psychres.2022.114890. Epub 2022 Oct 8.
The SARS-CoV-2 (COVID-19) pandemic has increased healthcare worker (HCW) susceptibility to mental illness. We conducted a meta-analysis to investigate the prevalence and possible factors associated with post-traumatic stress disorder (PTSD) symptoms among HCW during the COVID-19 pandemic. We searched PubMed, SCOPUS and EMBASE databases up to May 4th, 2022. We performed random effects meta-analysis and moderator analyses for the prevalence of PTSD-relevant symptoms and severe PTSD symptoms. We identified 1276 studies, reviewed 209 full-text articles, and included 119 studies (117,143 participants) with a total of 121 data points in our final analysis. 34 studies (24,541 participants) reported prevalence of severe PTSD symptoms. Approximately 25.2% of participants were physicians, 42.8% nurses, 12.4% allied health professionals, 8.9% auxiliary health professionals, and 10.8% "other". The pooled prevalence of PTSD symptoms among HCWs was 34% (95% CI, 0.30-0.39, I >90%), and 14% for severe PTSD (95% CI, 0.11 - 0.17, I >90%). The introduction of COVID vaccines was associated with a sharp decline in the prevalence of PTSD, and new virus variants were associated with small increases in PTSD rates. It is important that policies work towards allocating adequate resources towards protecting the well-being of healthcare workers to minimize adverse consequences of PTSD.
SARS-CoV-2（COVID-19）大流行增加了医护人员（HCW）患精神疾病的易感性。我们进行了一项荟萃分析，以调查 COVID-19 大流行期间 HCW 中创伤后应激障碍（PTSD）症状的患病率和可能相关因素。我们检索了 PubMed、SCOPUS 和 EMBASE 数据库，截至 2022 年 5 月 4 日。我们对 PTSD 相关症状和严重 PTSD 症状的患病率进行了随机效应荟萃分析和调节因子分析。我们确定了 1276 项研究，审查了 209 篇全文文章，并在最终分析中纳入了 119 项研究（117143 名参与者），共 121 个数据点。34 项研究（24541 名参与者）报告了严重 PTSD 症状的患病率。大约 25.2%的参与者是医生，42.8%是护士，12.4%是辅助卫生专业人员，8.9%是辅助卫生专业人员，10.8%是“其他”。HCW 中 PTSD 症状的总患病率为 34%（95%CI，0.30-0.39，I >90%），严重 PTSD 的患病率为 14%（95%CI，0.11-0.17，I >90%）。COVID 疫苗的推出与 PTSD 患病率的急剧下降有关，新的病毒变体与 PTSD 率的小幅上升有关。重要的是，政策应致力于分配足够的资源来保护医护人员的福祉，以尽量减少 PTSD 的不利后果。
