一种在振荡剪切应力下测量红细胞变形性的新方法。

A novel method for measuring the erythrocyte deformability, under oscillatory shear stress.

作者信息

Kon K, Murakami J, Okazaki M, Shiga T

出版信息

Jpn J Physiol. 1987;37(2):337-40. doi: 10.2170/jjphysiol.37.337.

DOI:10.2170/jjphysiol.37.337

Abstract

A novel apparatus for detecting a subtle decrease in erythrocyte deformability was developed. The oscillatory shape change of erythrocytes was monitored under an oscillatory shear stress (modulating the oscillation frequency in the range of 9-90 dyn/cm2). The ellipsoidal deformation of intact erythrocytes perfectly followed the oscillatory force of up to about 2 Hz, but the diamide-treated cells showed a phase difference of the oscillatory deformation at 1.7 Hz.

摘要

开发了一种用于检测红细胞变形性细微下降的新型装置。在振荡剪切应力（将振荡频率调节在9 - 90达因/平方厘米范围内）下监测红细胞的振荡形状变化。完整红细胞的椭圆形变形能完美地跟随高达约2赫兹的振荡力，但经二酰胺处理的细胞在1.7赫兹时显示出振荡变形的相位差。