Department of Oral Medicine and Radiology, Saveetha Dental College and Hospitals, Chennai, India.
Department of Oral Medicine and Radiology, A. M. E'S Dental College and Hospital, Raichur, India.
Int J Clin Pract. 2022 Sep 30;2022:2826862. doi: 10.1155/2022/2826862. eCollection 2022.
Oral submucous fibrosis (OSMF) is a premalignant condition of insidious onset which affects the oral mucosa, pharynx, and esophagus. The muscles of mastication are known to be affected resulting in limited mouth opening. Electromyography (EMG) is a sophisticated method of measuring and evaluating muscle activity. Previously, EMG was primarily utilized in medical sciences, but it is currently being used extensively in both the medical and dentistry fields.
The aim of the study is to evaluate the electromyographic activity of masseter muscle in OSMF patients before and after treatment and to compare with healthy controls.
This prospective case-control clinical study comprised 180 OSMF patients who were divided into four groups and 45 healthy individuals served as the control group. The OSMF individuals were injected with hyaluronidase 1,500 IU mixed in 1.5 ml of dexamethasone and 0.5 ml of lignocaine HCL intralesionally twice a week for one month along with a basic physiotherapy regimen consisting of mouth exercises two times daily. The control subjects were given placebo capsules. The treatment was carried out for a month and the electromyographic masseter muscle activity was evaluated among the OSMF patients and control group before and after treatment.
The results revealed that the electromyographic activity of master muscles in OSMF patients showed increased activity when compared with healthy controls. Patients with OSMF showed decreased muscle activity after treatment.
When compared with healthy controls, OSMF patients had higher electromyographic activity of the masseter muscles and the muscle activity was decreased following treatment. In OSMF patients, EMG may help in determining the involvement of the mastication and facial expression muscles. It can also be used as a diagnostic tool to assess the treatment outcome of muscle activity in OSMF patients.
口腔黏膜下纤维性变（OSMF）是一种起病隐匿的癌前状态，影响口腔黏膜、咽和食管。咀嚼肌已知受到影响，导致张口受限。肌电图（EMG）是一种测量和评估肌肉活动的复杂方法。以前，EMG 主要用于医学科学，但现在在医学和牙科领域都得到了广泛应用。
本研究旨在评估 OSMF 患者治疗前后咀嚼肌的肌电图活动，并与健康对照组进行比较。
这项前瞻性病例对照临床研究包括 180 名 OSMF 患者，他们被分为四组，45 名健康个体作为对照组。OSMF 个体每周两次接受 1,500IU 透明质酸酶混合在 1.5ml 地塞米松和 0.5ml 盐酸利多卡因的病灶内注射，同时进行包括每天两次口腔运动的基本物理治疗方案。对照组给予安慰剂胶囊。治疗进行了一个月，评估了 OSMF 患者和对照组治疗前后的咀嚼肌肌电图活动。
结果显示，与健康对照组相比，OSMF 患者的咀嚼肌肌电图活动增加。OSMF 患者治疗后肌肉活动减少。
与健康对照组相比，OSMF 患者的咀嚼肌肌电图活动较高，治疗后肌肉活动减少。在 OSMF 患者中，EMG 可能有助于确定咀嚼肌和面部表情肌的受累情况。它还可以用作评估 OSMF 患者肌肉活动治疗效果的诊断工具。
