Singh Nisha, Hebbale Manjula, Mhapuskar Amit, Ul Nisa Shams, Thopte Shameeka, Singh Saumya
Postgraduate Student, Department of Oral Medicine and Radiology, Bharati Vidyapeeth Deemed University, Dental College and Hospital, Pune 411043 Maharashtra, India, Phone: +8554857898, e-mail:
Department of Oral Medicine and Radiology, Bharati Vidyapeeth Deemed University, Dental College and Hospital Pune, Maharashtra, India.
J Contemp Dent Pract. 2016 Jan 1;17(1):78-84. doi: 10.5005/jp-journals-10024-1806.
Oral submucous fibrosis (OSMF) is a well-established precancerous condition affecting the oral mucosa. It is a disease that causes significant morbidity (in terms of loss of mouth function as tissues become rigid and mouth opening becomes difficult) and mortality (when transformation into squamous cell carcinoma occurs).
The aim of the study is to compare the efficacy of Aloe vera with antioxidant when given along with physiotherapy in the management of OSMF.
Forty patients presenting with clinical signs and symptoms of OSMF were included for the study after informed consent. Group A included 20 patients who received Aloe vera gel (forever living gel) along with physiotherapy. Group B included 20 patients who received antioxidant capsules twice daily for 3 months along with physiotherapy exercises four times in a day. The following parameters, that is, burning sensation, mouth opening, tongue protrusion and cheek flexibility were recorded at each visit.
Majority of the participant enrolled were in the age range of 30 to 35 years. Improvement in all the parameters was seen with the individuals receiving Aloe vera gel in comparison to antioxidants.
So, Aloe vera being a soothing, simple and safe mode of treatment along with proper habit restriction can be considered to be an effectual protocol in the management of OSMF. The analgesic effects of Aloe vera with the physiotherapy exercises provide better results in reducing burning sensation and improving mouth opening, tongue protrusion and cheek flexibility in comparison to antioxidants.
口腔黏膜下纤维化(OSMF)是一种已被确认的影响口腔黏膜的癌前病变。它是一种会导致严重发病率(由于组织变硬和张口困难导致口腔功能丧失)和死亡率(当转变为鳞状细胞癌时)的疾病。
本研究的目的是比较芦荟与抗氧化剂在联合物理治疗管理口腔黏膜下纤维化中的疗效。
40例有口腔黏膜下纤维化临床症状和体征的患者在获得知情同意后纳入研究。A组包括20例接受芦荟凝胶(永久活凝胶)联合物理治疗的患者。B组包括20例每天服用两次抗氧化剂胶囊,持续3个月,并每天进行4次物理治疗锻炼的患者。每次就诊时记录以下参数,即烧灼感、张口度、伸舌度和颊部柔韧性。
大多数纳入的参与者年龄在30至35岁之间。与接受抗氧化剂的个体相比,接受芦荟凝胶的个体在所有参数上均有改善。
因此,芦荟作为一种舒缓、简单且安全的治疗方式,结合适当的习惯限制,可被认为是口腔黏膜下纤维化管理中的一种有效方案。与抗氧化剂相比,芦荟与物理治疗锻炼的镇痛效果在减轻烧灼感、改善张口度、伸舌度和颊部柔韧性方面提供了更好的效果。