基于颈椎矢状位对线的全椎间盘置换改变颈椎生物力学:一项有限元研究。

Total disc replacement alters the biomechanics of cervical spine based on sagittal cervical alignment: A finite element study.

作者信息

Mumtaz Muzammil, Mendoza Justin, Tripathi Sudharshan, Kelkar Amey, Nishida Norihiro, Sahai Ashish, Goel Vijay K

机构信息

Department of Bioengineering and Orthopaedics Surgery, Engineering Center for Orthopaedic Research Excellence, College of Engineering and Medicine, The University of Toledo, Toledo, Ohio, USA.

Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Japan.

出版信息

J Craniovertebr Junction Spine. 2022 Jul-Sep;13(3):278-287. doi: 10.4103/jcvjs.jcvjs_21_22. Epub 2022 Sep 14.

Abstract

INTRODUCTION

The correlation between cervical alignment and clinical outcome of total disc replacement (TDR) surgery is arguable. We believe that this conflict exists because the parameters that influence the biomechanics of the cervical spine are not well understood, specifically the effect of TDR on different cervical alignments.

METHODS

A validated osseo-ligamentous model from C2-C7 was used in this study. The C2-C7 Cobb angle of the base model was modified to represent: lordotic (-10°), straight (0°), and kyphotic (+10°) cervical alignment. The TDR surgery was simulated at the C5-C6 segment. The range of motion (ROM), intradiscal pressure, annular stresses, and facet loads were computed for all the models.

RESULTS

The ROM results demonstrated kyphotic alignment after TDR surgery to be the most mobile when compared to intact base model (41% higher in flexion-extension, 51% higher in lateral bending, and 27% higher in axial rotation) followed by straight and lordotic alignment, respectively. The annular stresses for the kyphotic alignment when compared to intact base model were higher at the index level (33% higher in flexion-extension and 48% higher in lateral bending) compared to other alignments. The lordotic model demonstrated higher facet contact forces at the index level (75% higher in extension than kyphotic alignment, 51% higher in lateral bending than kyphotic alignment, and 78% higher in axial rotation than kyphotic alignment) when compared among the three alignment models.

CONCLUSION

Preoperative cervical alignment should be an integral part of surgical planning for TDR surgery as different cervical alignments may significantly alter the postsurgical outcomes.

摘要

引言

颈椎排列与全椎间盘置换(TDR)手术临床结果之间的相关性存在争议。我们认为这种争议的存在是因为影响颈椎生物力学的参数尚未得到充分理解,特别是TDR对不同颈椎排列的影响。

方法

本研究使用了经过验证的C2-C7节段的骨韧带模型。基础模型的C2-C7 Cobb角被修改以代表:前凸(-10°)、直型(0°)和后凸(+10°)颈椎排列。在C5-C6节段模拟TDR手术。计算所有模型的活动范围(ROM)、椎间盘内压力、纤维环应力和小关节负荷。

结果

ROM结果显示,与完整基础模型相比,TDR手术后后凸排列的活动度最大(屈伸时高41%,侧屈时高51%,轴向旋转时高27%),其次分别是直型和前凸排列。与完整基础模型相比,后凸排列在索引节段的纤维环应力在屈伸时更高(高33%),侧屈时更高(高48%)。在三种排列模型中比较时,前凸模型在索引节段显示出更高的小关节接触力(伸展时比后凸排列高75%,侧屈时比后凸排列高51%,轴向旋转时比后凸排列高78%)。

结论

术前颈椎排列应成为TDR手术规划的一个组成部分,因为不同的颈椎排列可能会显著改变术后结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/228ba57edc17/JCVJS-13-278-g001.jpg

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