• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

基于颈椎矢状位对线的全椎间盘置换改变颈椎生物力学：一项有限元研究。

Total disc replacement alters the biomechanics of cervical spine based on sagittal cervical alignment: A finite element study.

作者信息

Mumtaz Muzammil, Mendoza Justin, Tripathi Sudharshan, Kelkar Amey, Nishida Norihiro, Sahai Ashish, Goel Vijay K

机构信息

Department of Bioengineering and Orthopaedics Surgery, Engineering Center for Orthopaedic Research Excellence, College of Engineering and Medicine, The University of Toledo, Toledo, Ohio, USA.

Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Japan.

出版信息

J Craniovertebr Junction Spine. 2022 Jul-Sep;13(3):278-287. doi: 10.4103/jcvjs.jcvjs_21_22. Epub 2022 Sep 14.

DOI:10.4103/jcvjs.jcvjs_21_22
PMID:36263350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9574107/
Abstract

INTRODUCTION

The correlation between cervical alignment and clinical outcome of total disc replacement (TDR) surgery is arguable. We believe that this conflict exists because the parameters that influence the biomechanics of the cervical spine are not well understood, specifically the effect of TDR on different cervical alignments.

METHODS

A validated osseo-ligamentous model from C2-C7 was used in this study. The C2-C7 Cobb angle of the base model was modified to represent: lordotic (-10°), straight (0°), and kyphotic (+10°) cervical alignment. The TDR surgery was simulated at the C5-C6 segment. The range of motion (ROM), intradiscal pressure, annular stresses, and facet loads were computed for all the models.

RESULTS

The ROM results demonstrated kyphotic alignment after TDR surgery to be the most mobile when compared to intact base model (41% higher in flexion-extension, 51% higher in lateral bending, and 27% higher in axial rotation) followed by straight and lordotic alignment, respectively. The annular stresses for the kyphotic alignment when compared to intact base model were higher at the index level (33% higher in flexion-extension and 48% higher in lateral bending) compared to other alignments. The lordotic model demonstrated higher facet contact forces at the index level (75% higher in extension than kyphotic alignment, 51% higher in lateral bending than kyphotic alignment, and 78% higher in axial rotation than kyphotic alignment) when compared among the three alignment models.

CONCLUSION

Preoperative cervical alignment should be an integral part of surgical planning for TDR surgery as different cervical alignments may significantly alter the postsurgical outcomes.

摘要

引言

颈椎排列与全椎间盘置换（TDR）手术临床结果之间的相关性存在争议。我们认为这种争议的存在是因为影响颈椎生物力学的参数尚未得到充分理解，特别是TDR对不同颈椎排列的影响。

方法

本研究使用了经过验证的C2-C7节段的骨韧带模型。基础模型的C2-C7 Cobb角被修改以代表：前凸（-10°）、直型（0°）和后凸（+10°）颈椎排列。在C5-C6节段模拟TDR手术。计算所有模型的活动范围（ROM）、椎间盘内压力、纤维环应力和小关节负荷。

结果

ROM结果显示，与完整基础模型相比，TDR手术后后凸排列的活动度最大（屈伸时高41%，侧屈时高51%，轴向旋转时高27%），其次分别是直型和前凸排列。与完整基础模型相比，后凸排列在索引节段的纤维环应力在屈伸时更高（高33%），侧屈时更高（高48%）。在三种排列模型中比较时，前凸模型在索引节段显示出更高的小关节接触力（伸展时比后凸排列高75%，侧屈时比后凸排列高51%，轴向旋转时比后凸排列高78%）。

结论

术前颈椎排列应成为TDR手术规划的一个组成部分，因为不同的颈椎排列可能会显著改变术后结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/ef00f7c06706/JCVJS-13-278-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/228ba57edc17/JCVJS-13-278-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/8605922e9953/JCVJS-13-278-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/330dcf75a90e/JCVJS-13-278-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/664d2807528a/JCVJS-13-278-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/a75e349487a7/JCVJS-13-278-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/fa2ffe105986/JCVJS-13-278-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/bdd4bee204b4/JCVJS-13-278-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/4455d9589a63/JCVJS-13-278-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/bd5eebb2ee88/JCVJS-13-278-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/41b37775c9d5/JCVJS-13-278-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/da7aaacc310a/JCVJS-13-278-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/a7ff58147ca2/JCVJS-13-278-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/029496096b05/JCVJS-13-278-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/2d86c3d64e78/JCVJS-13-278-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/4d3f77056a4e/JCVJS-13-278-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/720963b67675/JCVJS-13-278-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/ab5163a2ea3d/JCVJS-13-278-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/ef00f7c06706/JCVJS-13-278-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/228ba57edc17/JCVJS-13-278-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/8605922e9953/JCVJS-13-278-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/330dcf75a90e/JCVJS-13-278-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/664d2807528a/JCVJS-13-278-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/a75e349487a7/JCVJS-13-278-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/fa2ffe105986/JCVJS-13-278-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/bdd4bee204b4/JCVJS-13-278-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/4455d9589a63/JCVJS-13-278-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/bd5eebb2ee88/JCVJS-13-278-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/41b37775c9d5/JCVJS-13-278-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/da7aaacc310a/JCVJS-13-278-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/a7ff58147ca2/JCVJS-13-278-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/029496096b05/JCVJS-13-278-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/2d86c3d64e78/JCVJS-13-278-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/4d3f77056a4e/JCVJS-13-278-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/720963b67675/JCVJS-13-278-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/ab5163a2ea3d/JCVJS-13-278-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/9574107/ef00f7c06706/JCVJS-13-278-g018.jpg

相似文献

1
Total disc replacement alters the biomechanics of cervical spine based on sagittal cervical alignment: A finite element study.基于颈椎矢状位对线的全椎间盘置换改变颈椎生物力学：一项有限元研究。
J Craniovertebr Junction Spine. 2022 Jul-Sep;13(3):278-287. doi: 10.4103/jcvjs.jcvjs_21_22. Epub 2022 Sep 14.
2
Biomechanical Analysis of the Cervical Spine Following Disc Degeneration, Disc Fusion, and Disc Replacement: A Finite Element Study.椎间盘退变、椎间盘融合和椎间盘置换后颈椎的生物力学分析：一项有限元研究
Int J Spine Surg. 2019 Dec 31;13(6):491-500. doi: 10.14444/6066. eCollection 2019 Dec.
3
Kinematics of cervical total disc replacement adjacent to a two-level, straight versus lordotic fusion.颈椎全椎间盘置换相邻两节段的运动学：直型与前凸型融合的对比。
Spine (Phila Pa 1976). 2011 Aug 1;36(17):1359-66. doi: 10.1097/BRS.0b013e318222d4ad.
4
Effect of two-level total disc replacement on cervical spine kinematics.双节段全椎间盘置换对颈椎运动学的影响。
Spine (Phila Pa 1976). 2009 Oct 15;34(22):E794-9. doi: 10.1097/BRS.0b013e3181afe4bb.
5
Biomechanical evaluation of a metal-on-metal cervical intervertebral disc prosthesis.金属对金属颈椎间盘假体的生物力学评估。
Spine J. 2013 Nov;13(11):1640-9. doi: 10.1016/j.spinee.2013.06.026. Epub 2013 Oct 2.
6
The Predictable Factors of the Postoperative Kyphotic Change of Sagittal Alignment of the Cervical Spine after the Laminoplasty.椎板成形术后颈椎矢状位排列术后后凸变化的可预测因素
J Korean Neurosurg Soc. 2017 Sep;60(5):577-583. doi: 10.3340/jkns.2017.0505.007. Epub 2017 Aug 30.
7
The effect of follower load on the range of motion, facet joint force, and intradiscal pressure of the cervical spine: a finite element study.追随者负载对颈椎活动范围、关节突关节力和椎间盘内压力的影响：一项有限元研究。
Med Biol Eng Comput. 2020 Aug;58(8):1695-1705. doi: 10.1007/s11517-020-02189-7. Epub 2020 May 28.
8
The biomechanical impact of facet tropism on the intervertebral disc and facet joints in the cervical spine.小关节面倾斜对颈椎间盘和小关节的生物力学影响。
Spine J. 2017 Dec;17(12):1926-1931. doi: 10.1016/j.spinee.2017.07.009. Epub 2017 Jul 13.
9
Using Finite Element Models to Assess Spinal Cord Biomechanics after Cervical Laminoplasty for Degenerative Cervical Myelopathy.使用有限元模型评估退变性颈椎病颈椎椎板成形术后脊髓生物力学
Diagnostics (Basel). 2024 Jul 12;14(14):1497. doi: 10.3390/diagnostics14141497.
10
Biomechanical analysis of laminectomy, laminoplasty, posterior decompression with instrumented fusion, and anterior decompression with fusion for the kyphotic cervical spine.后路单开门椎管扩大成形术与颈椎后路减压固定融合术治疗颈椎后凸畸形的生物力学比较
Int J Comput Assist Radiol Surg. 2022 Sep;17(9):1531-1541. doi: 10.1007/s11548-022-02692-2. Epub 2022 Jun 20.

引用本文的文献

1
Biomechanical Changes in Kyphotic Cervical Spine After Anterior Cervical Discectomy and Fusion with Different Degrees of Correction.前路颈椎间盘切除融合术不同程度矫正后颈椎后凸的生物力学变化
Bioengineering (Basel). 2025 Feb 20;12(3):213. doi: 10.3390/bioengineering12030213.

本文引用的文献

1
A Comparative Biomechanical Analysis of Various Rod Configurations Following Anterior Column Realignment and Pedicle Subtraction Osteotomy.前路椎体复位及经椎弓根截骨术后不同棒构型的比较生物力学分析
Neurospine. 2021 Sep;18(3):587-596. doi: 10.14245/ns.2142450.225. Epub 2021 Sep 30.
2
Cervical Spine Surgery: Arthroplasty Versus Fusion Versus Posterior Foraminotomy.颈椎手术：关节置换与融合与后路椎间孔切开术。
Neurosurg Clin N Am. 2021 Oct;32(4):483-492. doi: 10.1016/j.nec.2021.05.005.
3
Cervical Total Disc Replacement: Complications and Complication Avoidance.
颈椎全椎间盘置换：并发症与并发症预防。
Neurosurg Clin N Am. 2021 Oct;32(4):473-481. doi: 10.1016/j.nec.2021.05.006.
4
Ten-Year Outcomes of 1- and 2-Level Cervical Disc Arthroplasty From the Mobi-C Investigational Device Exemption Clinical Trial.Mobi-C 研究性设备豁免临床试验：1 至 2 节颈椎间盘置换术的 10 年结果。
Neurosurgery. 2021 Feb 16;88(3):497-505. doi: 10.1093/neuros/nyaa459.
5
A Comparison Study of Four Cervical Disk Arthroplasty Devices Using Finite Element Models.使用有限元模型对四种颈椎间盘置换装置的比较研究。
Asian Spine J. 2021 Jun;15(3):283-293. doi: 10.31616/asj.2020.0117. Epub 2020 Oct 29.
6
Influence of cervical spine sagittal alignment on range of motion after corpectomy: a finite element study.颈椎矢状位对线对椎体切除术后活动范围的影响：一项有限元研究。
Acta Neurochir (Wien). 2021 Jan;163(1):251-257. doi: 10.1007/s00701-020-04619-9. Epub 2020 Oct 23.
7
Cervical Sagittal Alignment: Literature Review and Future Directions.颈椎矢状位排列：文献综述与未来方向。
Neurospine. 2020 Sep;17(3):478-496. doi: 10.14245/ns.2040392.196. Epub 2020 Sep 30.
8
Clinical and radiological outcomes of single-level cervical disc arthroplasty in the patients with preoperative reversible kyphosis: A matched cohort study.术前可复性后凸患者行单节段颈椎间盘置换术的临床和影像学结果：一项配对队列研究。
Clin Neurol Neurosurg. 2020 Nov;198:106247. doi: 10.1016/j.clineuro.2020.106247. Epub 2020 Sep 23.
9
External and internal responses of cervical disc arthroplasty and anterior cervical discectomy and fusion: A finite element modeling study.颈椎间盘置换与前路颈椎间盘切除融合术后颈椎的内外反应：一项有限元建模研究。
J Mech Behav Biomed Mater. 2020 Jun;106:103735. doi: 10.1016/j.jmbbm.2020.103735. Epub 2020 Mar 22.
10
Cervical Disc Replacement: Trends, Costs, and Complications.颈椎间盘置换：趋势、成本与并发症
Asian Spine J. 2020 Oct;14(5):647-654. doi: 10.31616/asj.2019.0246. Epub 2020 Mar 30.