Department of Basic Sciences, Indian Institute of Information Technology Nagpur, Nagpur 441108, Maharashtra, India.
Department of Mathematics, SASTRA Deemed University, Thanjavur, Tamil Nadu 613401, India.
Comput Methods Programs Biomed. 2022 Nov;226:107156. doi: 10.1016/j.cmpb.2022.107156. Epub 2022 Sep 30.
Due to the low toxicity, unique physiochemical properties, and appropriate surface modifications, Carbon Nanotubes (CNTs) are used as target carriers in drug delivery systems. In the present problem, we have considered both single-walled and multi-walled CNTs to study the impact of irreversibility on the micropolar nanofluid flow through a squeezing channel with the base fluid blood. The blood is considered a micropolar fluid in the presence of different blood cells and their rotational nature. Further, blood is influenced by the external magnetic field parallel to the microrotation along with viscous and Joule dissipations.
Highly coupled and nonlinear partial differential equations are solved with Homotopy Analysis Method (HAM) after simplified equations using similarity transformation. Further, we have concluded the minimum squared residual errors to show the method's accuracy. A comparison made with the existing literature and shows a good agreement.
The angular velocity of the fluid particles is enhanced by increasing the squeezing number. In the case of the squeezing, volume fraction has improved the viscous drag and is found high for MWCNT embedded nanofluid. The heat transfer rate is higher for the MWCNT embedded nanofluid than the SWCNT embedded nanofluid. A descent found in entropy generation boosts up with the Brinkman parameter while opposite phenomena appear for radiation and Hartman number and vortex viscosity. Both Bejan number and entropy generation profiles are restricted with an increase in vortex viscosity.
SWCNTs are showed to be more effective and efficient than the MWCNTs in elevating velocity, temperature and irreversibility of the system. Outcomes of this problem will help to understand the implementation of the drug carrier and irreversibility phenomena during drug delivery.
由于毒性低、独特的物理化学性质和适当的表面修饰，碳纳米管（CNTs）被用作药物传递系统中的靶向载体。在本问题中，我们考虑了单壁和多壁 CNTs，以研究不可逆性对通过具有基底流体血液的挤压通道的微极纳米流体流动的影响。在存在不同的血细胞及其旋转性质的情况下，血液被认为是一种微极流体。此外，血液受到平行于微旋转的外加磁场的影响，同时存在粘性和焦耳耗散。
通过相似变换简化方程后，使用同伦分析方法（HAM）求解高度耦合和非线性偏微分方程。进一步，我们得出了最小二乘残差来表示方法的准确性。与现有文献的比较表明了良好的一致性。
通过增加挤压数来增强流体粒子的角速度。在挤压的情况下，体积分数提高了粘性阻力，在嵌入 MWCNT 的纳米流体中发现较高。MWCNT 嵌入纳米流体的传热速率高于 SWCNT 嵌入纳米流体。随着 Brinkman 参数的增加，熵产生的下降增加，而辐射和 Hartman 数和涡粘度则出现相反的现象。随着涡粘度的增加，两个 Bejan 数和熵产生分布都受到限制。
SWCNTs 在提高速度、温度和系统的不可逆性方面比 MWCNTs 更有效和高效。本问题的结果将有助于理解药物载体的实施和药物传递过程中的不可逆性现象。
