Devaux F, Herbelin P, Acezat F, Goizel C
J Pharmacol Methods. 1987 Aug;18(1):69-80. doi: 10.1016/0160-5402(87)90018-0.
A complete system is described for the computerized automation of the determination of activity of hypertensive drugs in the anesthetized rat. The microcomputer used was the Apple IIe, and the automation was performed by a purpose-designed command module. The series of injections of hypertensive drugs was controlled by the microcomputer through the intermediary of the command module. All processing of the signal (hypertension peak), calculation of the data obtained, statistical processing, and archive storage of the results was carried out entirely by the microcomputer. The computer was able unaided to control three work stations simultaneously without requiring synchronization.
描述了一种用于在麻醉大鼠中实现高血压药物活性测定计算机自动化的完整系统。所使用的微型计算机是苹果IIe型,自动化由专门设计的命令模块执行。高血压药物的一系列注射由微型计算机通过命令模块进行控制。信号(高血压峰值)的所有处理、所得数据的计算、统计处理以及结果的存档存储均完全由微型计算机完成。该计算机能够在无需同步的情况下独立同时控制三个工作站。