Department of Anaesthesiology, the Centre for Cancer and Organ Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Biomedical Signal Processing & AI Research Group, Digital Health Section, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.
Acta Anaesthesiol Scand. 2023 Jan;67(1):19-28. doi: 10.1111/aas.14158. Epub 2022 Nov 1.
Postoperative deviating physiologic values (vital signs) may represent postoperative stress or emerging complications. But they can also reflect chronic preoperative values. Distinguishing between the two circumstances may influence the utility of using vital signs in patient monitoring. Thus, we aimed to describe the occurrence of vital sign deviations before and after major vascular surgery, hypothesising that preoperative vital sign deviations were longer in duration postoperatively.
In this prospective observational study, arterial vascular patients were continuously monitored wirelessly - from the day before until 5 days after surgery. Recorded values were: heart rate, respiration rate, peripheral arterial oxygen saturation (SpO ) and blood pressure. The outcomes were 1. cumulative duration of SpO < 85% / 24 h, and 2. cumulative duration per 24 h of vital sign deviations.
Forty patients were included with a median monitoring time of 21 h preoperatively and 42 h postoperatively. The median duration of SpO < 85% preoperatively was 14.4 min/24 h whereas it was 28.0 min/24 h during day 0 in the ward (p = .09), and 16.8 min/24 h on day 1 in the ward (p = 0.61). Cumulative duration of SpO < 80% was significantly longer on day 0 in the ward 2.4 min/24 h (IQR 0.0-4.6) versus 6.7 min/24 h (IQR 1.8-16.2) p = 0.01.
Deviating physiology is common in patients before and after vascular surgery. A longer duration of severe desaturation was found on the first postoperative day in the ward compared to preoperatively, whereas moderate desaturations were reflected in postoperative desaturations. Cumulative duration outside thresholds is, in some cases, exacerbated after surgery.
术后偏离生理值(生命体征)可能代表术后应激或新出现的并发症。但它们也可能反映出慢性术前值。区分这两种情况可能会影响生命体征在患者监测中的应用效果。因此,我们旨在描述大血管手术后生命体征偏差的发生情况,假设术前生命体征偏差在术后持续时间更长。
在这项前瞻性观察研究中,对动脉血管患者进行连续无线监测 - 从手术前一天直到手术后 5 天。记录的数值包括:心率、呼吸频率、外周动脉血氧饱和度(SpO )和血压。主要结局为:1. 24 小时内 SpO < 85%的累计持续时间,2. 24 小时内每项生命体征偏差的累计持续时间。
共纳入 40 例患者,术前监测中位数为 21 小时,术后中位数为 42 小时。术前 SpO < 85%的中位持续时间为 14.4 分钟/24 小时,而术后第 0 天在病房中为 28.0 分钟/24 小时(p = 0.09),术后第 1 天在病房中为 16.8 分钟/24 小时(p = 0.61)。术后第 0 天病房中 SpO < 80%的累计持续时间明显更长,为 2.4 分钟/24 小时(IQR 0.0-4.6),而 6.7 分钟/24 小时(IQR 1.8-16.2),p = 0.01。
血管手术后患者的生理状态通常会发生偏离。与术前相比,术后第 1 天在病房中发现严重低氧血症的持续时间更长,而中度低氧血症则反映在术后低氧血症中。在某些情况下,术后阈值外的累计持续时间会加剧。