含硼吡唑化合物作为用于治疗炎症、自身免疫性疾病和癌症的JAK抑制剂
Boron-Containing Pyrazole Compounds as JAK Inhibitors for Treating Inflammation, Autoimmune Diseases, and Cancer.
作者信息
Sabnis Ram W
机构信息
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia30309, United States.
出版信息
ACS Med Chem Lett. 2022 Sep 5;13(10):1554-1555. doi: 10.1021/acsmedchemlett.2c00407. eCollection 2022 Oct 13.
Abstract
Provided herein are novel boron-containing pyrazole compounds as JAK inhibitors, pharmaceutical compositions, use of such compounds in treating inflammation, autoimmune diseases, and cancer, and processes for preparing such compounds.
摘要
本文提供了作为JAK抑制剂的新型含硼吡唑化合物、药物组合物、此类化合物在治疗炎症、自身免疫性疾病和癌症中的用途，以及制备此类化合物的方法。
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