骨质疏松症患者的生活质量。
Quality of Life in osteoporotic patients.
作者信息
Rizzo Maria, Tammaro Gisella, Guarino Amedeo, Basso Morena, Cozzolino Andrea, Mariconda Massimo
机构信息
Department of Public Health - Section of Orthopaedic Surgery - "Federico II" University - Naples (Italy).
出版信息
Orthop Rev (Pavia). 2022 Oct 13;14(6):38562. doi: 10.52965/001c.38562. eCollection 2022.
BACKGROUND
Osteoporosis is responsible for fragility fractures, which are associated with impaired quality of life (QoL) and disability.
OBJECTIVE
The aim of the study was to evaluate the QoL in patients affected by osteoporosis and possible determinants.
METHODS
One-hundred thirty-four subjects followed at the osteoprosis outpatient clinic at our institution completed the QUALEFFO-41 questionnaire for quality of life. All subjects had undergone bone densitometry measurement and the FRAX index, summarizing the risk of fragility fracture, was calculated for each of them. The QoL in these subjects and its possible determinants were investigated with univariate and multiple linear regression analysis.
RESULTS
Subjects with osteoporosis had lower scores in the domains of physical and social function of the QUALEFFO questionnaire in comparison with subjects with normal bome mineral density. Main factors associated with impairment in QoL were high FRAX score and body mass index (BMI).
CONCLUSION
Physical and social function is reduced in osteoporotic subjects. High BMI and an increased risk of fragility fracture were main determinants of impairment in the QoL in this study.
背景
骨质疏松症会导致脆性骨折，这与生活质量（QoL）受损和残疾相关。
目的
本研究的目的是评估骨质疏松症患者的生活质量及其可能的决定因素。
方法
在我们机构的骨质疏松门诊随访的134名受试者完成了用于评估生活质量的QUALEFFO - 41问卷。所有受试者均接受了骨密度测量，并为每个人计算了总结脆性骨折风险的FRAX指数。通过单因素和多元线性回归分析研究这些受试者的生活质量及其可能的决定因素。
结果
与骨矿物质密度正常的受试者相比，骨质疏松症患者在QUALEFFO问卷的身体和社会功能领域得分较低。与生活质量受损相关的主要因素是高FRAX评分和体重指数（BMI）。
结论
骨质疏松症患者的身体和社会功能降低。高BMI和脆性骨折风险增加是本研究中生活质量受损的主要决定因素。
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