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比较接受新生儿戒断综合征监测的药物治疗和非药物治疗婴儿的不良心肺事件的初步研究。

Pilot Study Comparing Adverse Cardiorespiratory Events among Pharmacologically and Nonpharmacologically Treated Infants Undergoing Monitoring for Neonatal Abstinence Syndrome.

作者信息

Davala Spoorthi, Hansbury Aaron, Miller Melissa, Boateng Jeffery, Shrestha Hira, Wachman Elisha M

机构信息

Boston University School of Medicine, Boston Medical Center, Boston, MA.

Boston University School of Public Health, Boston Medical Center, Boston, MA.

出版信息

J Pediatr X. 2020 Summer;3. doi: 10.1016/j.ympdx.2020.100027. Epub 2020 May 16.

DOI:10.1016/j.ympdx.2020.100027
PMID:36268268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9581337/
Abstract

There is variation in cardiorespiratory monitoring practices for neonatal abstinence syndrome. We examined the incidence of cardiorespiratory adverse events in infants with neonatal abstinence syndrome who were treated or nontreated pharmacologically. Eight (10%) in the nontreated and 23 (19%) in the treated group experienced adverse events. This warrants further investigation in a larger cohort.

摘要

新生儿戒断综合征的心肺监测方法存在差异。我们研究了接受或未接受药物治疗的新生儿戒断综合征婴儿发生心肺不良事件的发生率。未治疗组中有8例（10%），治疗组中有23例（19%）发生了不良事件。这需要在更大的队列中进行进一步研究。

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本文引用的文献

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Acta Paediatr. 2019 Feb;108(2):208-217. doi: 10.1111/apa.14606. Epub 2018 Dec 6.
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Comparison of Safety and Efficacy of Methadone vs Morphine for Treatment of Neonatal Abstinence Syndrome: A Randomized Clinical Trial.美沙酮与吗啡治疗新生儿戒断综合征的安全性和疗效比较：一项随机临床试验。
JAMA Pediatr. 2018 Aug 1;172(8):741-748. doi: 10.1001/jamapediatrics.2018.1307.
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Quality improvement initiative to improve inpatient outcomes for Neonatal Abstinence Syndrome.提高新生儿戒断综合征患者住院疗效的质量改进措施。
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Association of Rooming-in With Outcomes for Neonatal Abstinence Syndrome: A Systematic Review and Meta-analysis.母婴同室与新生儿戒断综合征结局的关系：系统评价和荟萃分析。
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