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本文引用的文献

1
Trends in emergent diverticular disease management: a nationwide cohort study from 2009 to 2018.2009 年至 2018 年全国队列研究:急症憩室疾病管理的变化趋势。
Tech Coloproctol. 2021 May;25(5):549-558. doi: 10.1007/s10151-021-02423-w. Epub 2021 Mar 3.
2
Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial.腹腔镜冲洗与原发性切除术治疗急性穿孔性憩室炎:来自斯堪的纳维亚憩室炎(SCANDIV)随机临床试验的长期结果。
JAMA Surg. 2021 Feb 1;156(2):121-127. doi: 10.1001/jamasurg.2020.5618.
3
Cost-effectiveness of sigmoid resection with primary anastomosis or end colostomy for perforated diverticulitis: an analysis of the randomized Ladies trial.乙状结肠切除一期吻合术与末端结肠造口术治疗穿孔性憩室炎的成本效益:随机 Ladies 试验分析。
Br J Surg. 2020 Nov;107(12):1686-1694. doi: 10.1002/bjs.11715. Epub 2020 Jun 10.
4
Pelvic Anastomosis Without Protective Ileostomy is Safe in Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.在接受细胞减灭术和腹腔热灌注化疗的患者中,不预防性行回肠造口术的盆腔吻合是安全的。
Ann Surg Oncol. 2020 Dec;27(13):4931-4940. doi: 10.1245/s10434-020-08479-6. Epub 2020 Jun 6.
5
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis.美国结肠和直肠外科医师协会左侧结肠憩室炎治疗临床实践指南。
Dis Colon Rectum. 2020 Jun;63(6):728-747. doi: 10.1097/DCR.0000000000001679.
6
2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting.2020 年 WSES 急性结肠憩室炎急诊处理指南更新版。
World J Emerg Surg. 2020 May 7;15(1):32. doi: 10.1186/s13017-020-00313-4.
7
Body image mediates the effect of stoma status on psychological distress and quality of life in patients with colorectal cancer.体像在结直肠癌患者造口状态对心理困扰和生活质量的影响中起中介作用。
Psychooncology. 2020 Apr;29(4):796-802. doi: 10.1002/pon.5352. Epub 2020 Feb 21.
8
Primary resection anastomosis versus Hartmann's procedure in Hinchey III and IV diverticulitis.Hinchey III 和 IV 型憩室炎行一期切除吻合术与 Hartmann 手术的比较。
World J Emerg Surg. 2019 Jul 11;14:32. doi: 10.1186/s13017-019-0251-4. eCollection 2019.
9
EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice.EAES 和 SAGES 2018 急性憩室炎管理共识会议:临床实践的循证推荐。
Surg Endosc. 2019 Sep;33(9):2726-2741. doi: 10.1007/s00464-019-06882-z. Epub 2019 Jun 27.
10
Hartmann's procedure versus sigmoidectomy with primary anastomosis for perforated diverticulitis with purulent or faecal peritonitis (LADIES): a multicentre, parallel-group, randomised, open-label, superiority trial.Hartmann 手术与一期吻合术治疗伴有脓性或粪便性腹膜炎的穿孔性憩室炎(LADIES):一项多中心、平行组、随机、开放标签、优效性试验。
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评估手工缝合全环加固的一期吻合术治疗左侧结肠穿孔性憩室炎的疗效。

Evaluating the outcomes of primary anastomosis with hand-sewn full-circular reinforcement in managing perforated left-sided colonic diverticulitis.

作者信息

Aoki Hikaru, Yamanaka Kenya, Kurimoto Makoto, Hanabata Yusuke, Shinkura Akina, Harada Kaichiro, Kayano Masashi, Tashima Misaki, Tamura Jun

机构信息

Department of Surgery, Hyogo Prefectural Amagasaki General Medical Center, 2-17-77, Higashinaniwa, Amagasaki, Hyogo, Japan.

出版信息

Ann Med Surg (Lond). 2022 Sep 22;82:104728. doi: 10.1016/j.amsu.2022.104728. eCollection 2022 Oct.

DOI:10.1016/j.amsu.2022.104728
PMID:36268302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9577872/
Abstract

BACKGROUND

It is a challenge to avoid stoma formation in emergency surgery of perforated left-sided diverticulum. The hand-sewn full-circular reinforcement of the colorectal anastomosis is used during complete pelvic peritonectomy to avoid a diverting ileostomy. This study examined the effect of applying the reinforcement method to perforated left-sided colonic diverticulitis with respect to the permanent stoma rate and cost-effectiveness.

MATERIALS AND METHODS

This historical cohort study examined all patients who underwent emergency surgery for perforation of a left-sided diverticulum at the Hyogo Prefectural Amagasaki General Medical Center between July 2015 and September 2019. The cohort was divided into two groups: those who underwent conventional method (Group F) and those for whom the hand-sewn full-circular reinforcement method was actively performed (Group L).

RESULTS

The number of patients who underwent emergency surgery which did not lead to an ostomy increased significantly from 12% (3/25) in Group F to 42% (11/26) in Group L (P = 0.0015). The rate of permanent stoma decreased from 80% in Group F to 27% in Group L (P < 0.001). Total treatment costs for patients under the age of 80 in Group L were significantly lower than those in Group F (2170000 ± 1020000 vs 3270000 ± 1960000 JPY; P = 0.018).

CONCLUSIONS

In emergency surgery for left-sided perforated colonic diverticulitis, applying the hand-sewn full-circle reinforcement of the anastomotic site may reduce stoma formation at the initial surgery and consequently decrease permanent stoma rate and contribute to cost-effectiveness without increasing complications such as anastomotic leakage.

摘要

背景

在左侧穿孔性憩室的急诊手术中避免造口形成是一项挑战。在全盆腔切除术期间采用手工缝合的结肠直肠吻合口全周加固术以避免行转流性回肠造口术。本研究探讨了应用该加固方法对左侧穿孔性结肠憩室炎患者永久造口率及成本效益的影响。

材料与方法

这项历史性队列研究纳入了2015年7月至2019年9月间在兵库县尼崎市立综合医疗中心接受左侧憩室穿孔急诊手术的所有患者。该队列分为两组:接受传统方法治疗的患者(F组)和积极采用手工缝合全周加固方法治疗的患者(L组)。

结果

未行造口的急诊手术患者数量从F组的12%(3/25)显著增加至L组的42%(11/26)(P = 0.0015)。永久造口率从F组的80%降至L组的27%(P < 0.001)。L组80岁以下患者的总治疗费用显著低于F组(2170000 ± 1020000日元 vs 3270000 ± 1960000日元;P = 0.018)。

结论

在左侧穿孔性结肠憩室炎的急诊手术中,应用吻合口手工缝合全周加固术可能会减少初次手术时的造口形成,从而降低永久造口率,并在不增加诸如吻合口漏等并发症的情况下提高成本效益。