AlZaabi Adhari, AlHarrasi Amna, AlMusalami Atika, AlMahyijari Nawal, Al Hinai Khalid, ALAdawi Humaid, Al-Shamsi Humaid O
Sultan Qaboos University, Sultanate of Oman.
Sultan Qaboos Comprehensive Cancer Care and Research Center, Sultanate of Oman.
Ann Med Surg (Lond). 2022 Aug 22;82:104453. doi: 10.1016/j.amsu.2022.104453. eCollection 2022 Oct.
Early Onset Colorectal cancer (EOCRC) incidence is increasing at an alarming pace. An increase of 90% in colon cancer and 124% in rectal cancer is expected by 2030. Patients with EOCRC are not receiving additional attention compared to older patients despite having a unique molecular pattern, majority of cases are sporadic, and related short- and long-term treatment and disease complications. The current management and screening guidelines have been constructed from studies on late onset CRC. Plethora of studies are ongoing to understand this disease entity in order to construct a tailored prevention, detection and management plans. While waiting for a better understanding of the disease, efforts should be directed toward improving the quality of care across the cancer continuum. Here we aim to address the challenges faced by EOCRC patients across the cancer continuum. This will facilitate directing future efforts and research toward construction of a personalized and precise guidelines.
早发性结直肠癌（EOCRC）的发病率正以惊人的速度上升。预计到2030年，结肠癌发病率将增加90%，直肠癌发病率将增加124%。与老年患者相比，EOCRC患者尽管具有独特的分子模式、大多数病例为散发性以及相关的短期和长期治疗及疾病并发症，但并未得到额外关注。目前的管理和筛查指南是基于对晚发性结直肠癌的研究制定的。目前正在进行大量研究以了解这一疾病实体，以便制定量身定制的预防、检测和管理计划。在等待对该疾病有更好了解的同时，应努力提高整个癌症连续过程中的护理质量。在此，我们旨在解决EOCRC患者在整个癌症连续过程中面临的挑战。这将有助于引导未来的努力和研究方向，以构建个性化和精确的指南。
