H.E.C. Science Clinic, Kanagawa, Japan.
Kawai Clinic, Ibaraki, Japan.
J Diabetes Investig. 2023 Jan;14(1):75-80. doi: 10.1111/jdi.13922. Epub 2022 Oct 21.
We assessed the prescription patterns of oral antidiabetic drugs in Japanese patients with type 2 diabetes between 2002 and 2020 using data from the Computerized Diabetes Care database. Among 172,960 patients treated with oral antidiabetic drugs, both the sulfonylurea prescription rate and dose decreased from 2002 to 2020. Prescriptions of biguanides, dipeptidyl peptidase-4 inhibitors and sodium-glucose cotransporter 2 inhibitors increased; their dose and dose frequency remained relatively stable. Trends in oral antidiabetic drug prescriptions changed over time, reflecting guideline recommendations and existing evidence.
我们利用 Computerized Diabetes Care 数据库中的数据，评估了 2002 年至 2020 年期间日本 2 型糖尿病患者口服降糖药的处方模式。在 172960 例接受口服降糖药治疗的患者中，磺脲类药物的处方率和剂量均呈下降趋势。双胍类、二肽基肽酶-4 抑制剂和钠-葡萄糖共转运蛋白 2 抑制剂的处方量增加，其剂量和剂量频率相对稳定。口服降糖药的处方趋势随时间而变化，反映了指南建议和现有证据。
