源自野生鸟类的H3N8亚型禽流感病毒呈现出双受体结合特征。
H3N8 subtype avian influenza virus originated from wild birds exhibited dual receptor-binding profiles.
作者信息
Tian Jingman, Li Minghui, Li Yulei, Bai Xiaoli, Song Xingdong, Zhao Zhiguo, Ge Shenfeng, Li Yuehui, Liu Jianwen, Shi Jianzhong, Wang Xiaoliang, Li Zhixin, Zhou Haining, Ma Long, Zeng Xianying, Tian Guobin, Guan Yuntao, Li Yanbing, Chen Hualan
机构信息
State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang province, China.
Preventive and Control Center for Animal Disease of Tianjin, China.
出版信息
J Infect. 2023 Feb;86(2):e36-e39. doi: 10.1016/j.jinf.2022.10.023. Epub 2022 Oct 20.
We present the phylogeny, receptor binding property, growth in mammal cells and pathogenicity in mammal model of H3N8 viruses, which were isolated from wild birds in China. The human receptor preference and efficient replication in mice without prior adaption highlight that the H3N8 virus possesses the public threat potential.
我们展示了从中国野生鸟类中分离出的H3N8病毒的系统发育、受体结合特性、在哺乳动物细胞中的生长情况以及在哺乳动物模型中的致病性。该H3N8病毒对人类受体的偏好以及在未经预先适应的情况下在小鼠体内的高效复制突出表明其具有公共威胁潜力。
Zotero 插件