Katowitz J A, Welsh M G
Ophthalmology. 1987 Jun;94(6):698-705. doi: 10.1016/s0161-6420(87)33392-5.
A series of 427 patients with congenital dacryostenosis involving 572 eyes was seen at the Children's Hospital of Philadelphia. All patients were treated conservatively with antibiotics and massage prior to decision by the parents to request probing. Congenital dacryostenosis, as well as resolution of symptoms, were confirmed by clinical examination and use of a modified dye disappearance test. In 572 eyes, the success rate of initial probing was found to be 97% under 13 months of age. Over 13 months, however, the mean success rate was found to be 54.7%. When broken down into smaller age categories, a stepwise progression was observed from 76.4% between 13 and 18 months to 33.3% for patients probed after 24 months. In addition, the number and complexity of subsequent procedures appeared to increase along with the age at which the initial probing was performed. These data suggest that initial probing should be done prior to 13 months of age depending on the severity of symptoms and parent compliance with medical management.
费城儿童医院共接诊了427例患有先天性泪道狭窄的患者,累及572只眼睛。在家长决定要求进行泪道探通术之前,所有患者均接受了抗生素治疗和按摩等保守治疗。通过临床检查和改良的染料消失试验确认了先天性泪道狭窄以及症状的缓解情况。在572只眼中,发现13个月以下患儿初次泪道探通术的成功率为97%。然而,13个月以上患儿的平均成功率为54.7%。当进一步细分年龄组时,观察到成功率呈逐步下降趋势,从13至18个月患儿的76.4%降至24个月后接受泪道探通术患儿的33.3%。此外,后续手术的次数和复杂性似乎随着初次泪道探通术时的年龄增加而增加。这些数据表明,应根据症状的严重程度以及家长对医疗管理的依从性,在13个月龄之前进行初次泪道探通术。