Kim Y S, Moon S C, Yoo K W
Department of Ophthalmology, School of Medicine, Chungnam National University Hospital, #640, Daesa-Dong, Jung-Gu, Taejon 301-721, Korea.
Korean J Ophthalmol. 2000 Dec;14(2):90-6. doi: 10.3341/kjo.2000.14.2.90.
The authors investigated the efficacy of antibiotic irrigation as the therapeutic option in congenital nasolacrimal duct obstruction. We retrospectively reviewed the medical record of 76 patients' eyes in whom congenital nasolacrimal duct obstruction had been diagnosed. In 50 of these patients, the colonizing microorganism was identified and, irrigation through canaliculi was performed using antibiotics of suitable sensitivity. Nasolacrimal system probing was performed on 26 patients as the control group. Treatment was regarded successful when over a 4 week period epiphora or mucous discharge disappeared and when saline passed without resistance on irrigation. 96.0% of patients in the irrigation group and 84.6% of patients in probing group were treated successfully. There was no statistical difference in the success rate between the two groups (P = 0.173). The recovery period based on culture results was 3.22 +/- 0.37 months in the group in which microorganisms were isolated and 2.39 +/- 0.35 months in the group in which no organisms were isolated. There were no statistically significant differences in the success rates between the group in which there was growth and the group in which there was no growth (P = 0.1308). Thus a similar result was obtained using nasolacrimal probing and canaliculus antibiotic irrigation in congenital nasolacrimal duct obstruction. Antibiotic irrigation is a safe and simple therapeutic option in congenital nasolacrimal duct obstruction.
作者研究了抗生素冲洗作为先天性鼻泪管阻塞治疗方法的疗效。我们回顾性分析了76例诊断为先天性鼻泪管阻塞患者的眼部病历。其中50例患者确定了定植微生物，并使用敏感性合适的抗生素通过泪小管进行冲洗。26例患者作为对照组进行鼻泪管探通术。当在4周内溢泪或黏液分泌物消失，且冲洗生理盐水时无阻力通过，则视为治疗成功。冲洗组96.0%的患者和探通组84.6%的患者治疗成功。两组成功率无统计学差异（P = 0.173）。根据培养结果，分离出微生物的组恢复期为3.22±0.37个月，未分离出微生物的组为2.39±0.35个月。有微生物生长组和无微生物生长组的成功率无统计学显著差异（P = 0.1308）。因此，在先天性鼻泪管阻塞中，鼻泪管探通术和泪小管抗生素冲洗取得了相似的结果。抗生素冲洗是先天性鼻泪管阻塞一种安全、简单的治疗方法。
