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妊娠背景下的创伤性肉毒中毒:文献综述与病例报告

Wound Botulism in the Setting of Pregnancy: A Literature Review and Case Report.

作者信息

Ghantarchyan Henrik, Phan Alexander T, Hu Janie, Thaker Kunal, Dombrovsky Inessa, Roloff Kristina, Arabian Sarkis

机构信息

Internal Medicine, Arrowhead Regional Medidcal Center, Colton, USA.

Internal Medicine, California University of Science and Medicine, Colton, USA.

出版信息

Cureus. 2022 Sep 17;14(9):e29273. doi: 10.7759/cureus.29273. eCollection 2022 Sep.

Abstract

Botulism is a rare neuroparalytic illness caused by that can manifest as a descending flaccid paralysis, progressing from cranial neuropathies to respiratory failure. Wound botulism, constituting a minority of cases, is majorly associated with the injection of black tar heroin (BTH) in the western United States. A patient population of particular concern is pregnant women, who may experience a more severe course due to the physiological changes that occur in pregnancy. Because botulism in pregnancy lacks pathognomic features, physicians should maintain a high clinical suspicion when faced with a pregnant patient with neurological symptoms and a history of BTH use. Here, we report the case of a 25-year-old G3P1A1 female with a history of BTH use who presented with cranial neuropathies and respiratory insufficiency.

摘要

肉毒中毒是一种由[具体病因未给出]引起的罕见神经麻痹性疾病,可表现为下行性弛缓性麻痹,从颅神经病变发展至呼吸衰竭。伤口型肉毒中毒占病例的少数,主要与美国西部注射黑色焦油海洛因(BTH)有关。特别值得关注的患者群体是孕妇,由于孕期发生的生理变化,她们可能经历更严重的病程。由于妊娠期肉毒中毒缺乏特征性表现,医生在面对有神经症状且有使用BTH病史的孕妇时应保持高度临床怀疑。在此,我们报告一例有BTH使用史的25岁G3P1A1女性患者,该患者出现颅神经病变和呼吸功能不全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e86/9576342/a7ad8ce6c842/cureus-0014-00000029273-i01.jpg

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