Hinohara Tomoya T, Reardon Michael J, Goel Sachin S
Department of Cardiology, Houston Methodist Hospital, Houston, TX, USA.
Department of Cardiovascular Surgery, DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX, USA.
Heart Int. 2021 Dec 20;15(2):79-83. doi: 10.17925/HI.2021.15.2.79. eCollection 2021.
Mitral regurgitation (MR) is the most prevalent valvular heart disease globally. Mitral valve surgery is the gold-standard treatment for MR. However, a significant portion of patients with mitral valve disease are at high or prohibitive surgical risk. Transcatheter mitral valve replacement (TMVR) has emerged as a potential treatment option for this vulnerable population. Numerous TMVR devices are currently being investigated, with early data demonstrating feasibility and efficacy of TMVR. In this article, we explore the unique challenges of designing a TMVR system and describe the TMVR systems under clinical evaluation.
二尖瓣反流(MR)是全球最常见的心脏瓣膜疾病。二尖瓣手术是治疗MR的金标准。然而,相当一部分二尖瓣疾病患者面临高手术风险或手术风险过高。经导管二尖瓣置换术(TMVR)已成为这一脆弱人群的一种潜在治疗选择。目前正在研究众多TMVR设备,早期数据表明TMVR具有可行性和有效性。在本文中,我们探讨了设计TMVR系统所面临的独特挑战,并描述了正在进行临床评估的TMVR系统。