Gardesevic Marina, Didikoglu Altug, Lawrence Samuel J D, Vetter Céline, Brown Timothy M, Allen Annette E, Lucas Robert J
Centre for Biological Timing, Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA.
Clocks Sleep. 2022 Oct 21;4(4):577-594. doi: 10.3390/clockssleep4040045.
Light is an influential regulator of behavioural and physiological state in mammals. Features of cognitive performance such as memory, vigilance and alertness can be altered by bright light exposure under laboratory and field conditions. However, the importance of light as a regulator of performance in everyday life is hard to assess and has so far remained largely unclear. We set out to address this uncertainty by developing a tool to capture measures of cognitive performance and light exposure, at scale, and during everyday life. To this end, we generated an app (Brighter Time) which incorporated a psychomotor vigilance (PVT), an N-back and a visual search task with questionnaire-based assessments of demographic characteristics, general health, chronotype and sleep. The app also measured illuminance during task completion using the smartphone's intrinsic light meter. We undertook a pilot feasibility study of Brighter Time based on 91-week-long acquisition phases within a convenience sample (recruited by local advertisements and word of mouth) running Brighter Time on their own smartphones over two study phases in winter and summer. Study compliance was suitable (median = 20/21 requested task completions per subject). Statistically significant associations were observed between subjective sleepiness and performance in all tasks. Significant daily variations in PVT and visual search performance were also observed. Higher illuminance was associated with reduced reaction time and lower inverse efficiency score in the visual search. Brighter Time thus represents a viable option for large-scale collection of cognitive task data in everyday life, and is able to reveal associations between task performance and sleepiness, time of day and current illuminance. Brighter Time's utility could be extended to exploring associations with longer-term patterns of light exposure and/or other light metrics by integrating with wearable light meters.
光对哺乳动物的行为和生理状态具有重要调节作用。在实验室和野外条件下,明亮光线照射可改变认知表现的特征,如记忆力、警觉性和机敏度。然而,光作为日常生活中表现调节因素的重要性难以评估,目前在很大程度上仍不明确。我们着手开发一种工具,以便在日常生活中大规模获取认知表现和光照暴露的测量数据,从而解决这一不确定性问题。为此,我们开发了一款应用程序(“更明亮时光”),它纳入了一项心理运动警觉性测试(PVT)、一项n-back测试和一项视觉搜索任务,以及基于问卷的人口统计学特征、总体健康状况、昼夜节律类型和睡眠情况评估。该应用程序还使用智能手机的内置光度计在任务完成期间测量照度。我们基于一个便利样本(通过当地广告和口口相传招募)进行了一项“更明亮时光”的试点可行性研究,该样本在冬季和夏季的两个研究阶段,在自己的智能手机上运行“更明亮时光”长达91周。研究依从性良好(每位受试者完成的任务中位数为20/21项要求完成的任务)。在所有任务中,主观困倦感与表现之间均观察到具有统计学意义的关联。PVT和视觉搜索表现也存在显著的每日变化。在视觉搜索中,较高的照度与较短的反应时间和较低的逆效率得分相关。因此,“更明亮时光”是在日常生活中大规模收集认知任务数据的可行选择,并且能够揭示任务表现与困倦感、一天中的时间以及当前照度之间的关联。通过与可穿戴光度计集成,“更明亮时光”的效用可扩展到探索与长期光照暴露模式和/或其他光照指标之间的关联。