University of Groningen, Chronobiology Unit, Groningen Institute for Evolutionary Life Sciences, Groningen, the Netherlands.
Chrono@Work, Groningen, the Netherlands.
J Biol Rhythms. 2018 Dec;33(6):637-648. doi: 10.1177/0748730418796036. Epub 2018 Sep 7.
Broad-spectrum light applied during the night has been shown to affect alertness in a dose-dependent manner. The goal of this experiment was to investigate whether a similar relationship could be established for light exposure during daytime. Fifty healthy participants were subjected to a paradigm (0730-1730 h) in which they were intermittently exposed to 1.5 h of dim light (<10 lux) and 1 h of experimental light (24-2000 lux). The same intensity of experimental light was used throughout the day, resulting in groups of 10 subjects per intensity. Alertness was assessed with subjective and multiple objective measures. A significant effect of time of day was found in all parameters of alertness ( p < 0.05). Significant dose-response relationships between light intensity and alertness during the day could be determined in a few of the parameters of alertness at some times of the day; however, none survived correction for multiple testing. We conclude that artificial light applied during daytime at intensities up to 2000 lux does not elicit significant improvements in alertness in non-sleep-deprived subjects.
夜间应用广谱光已被证明以剂量依赖的方式影响警觉度。本实验的目的是研究白天光照暴露是否也存在类似的关系。五十名健康参与者接受了一个范式(0730-1730 h)的实验,在此期间他们间歇性地暴露于 1.5 小时的低强度光(<10 lux)和 1 小时的实验光(24-2000 lux)。全天使用相同强度的实验光,导致每个强度组有 10 名参与者。通过主观和多项客观指标评估警觉度。在所有警觉度参数中(p<0.05)都发现了时间的显著影响。在白天的几个警觉度参数中,可以确定光强度与警觉度之间存在显著的剂量反应关系;然而,在多次测试校正后,没有一个关系仍然成立。我们得出结论,在非睡眠剥夺的受试者中,在白天应用强度高达 2000 lux 的人工光不会显著提高警觉度。