Pulmonary and Critical Care Division, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA; Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA.
Department of Epidemiology, Fay W. Boozman College Public Health, University of Arkansas for Medical Sciences, 4300 West Markham, Little Rock, AR 72205, USA.
Med Clin North Am. 2022 Nov;106(6):1093-1107. doi: 10.1016/j.mcna.2022.07.010. Epub 2022 Oct 4.
Human beings have used marijuana products for centuries. Relatively recent data showing extensive cannabinoid receptors, particularly in the brain, help to explain the impacts of cannabinoids on symptoms/diseases, such as pain and seizures, with major nervous system components. Marijuana can cause bronchitis, but a moderate body of literature suggests that distal airway/parenchymal lung disease does not occur; marijuana does not cause chronic obstructive pulmonary disease and probably does not cause lung cancer, distinctly different from tobacco. Potentials for cognitive impairment and for damage to the developing brain are contextually important as its beneficial uses are explored.
人类使用大麻制品已有几个世纪。最近的数据显示,广泛的大麻素受体,尤其是在大脑中,有助于解释大麻素对症状/疾病的影响,如疼痛和癫痫,这些症状/疾病与主要的神经系统成分有关。大麻会导致支气管炎,但相当多的文献表明,远端气道/实质肺疾病不会发生;大麻不会导致慢性阻塞性肺疾病,也可能不会导致肺癌,这与烟草明显不同。随着对大麻有益用途的探索,认知障碍和对发育中大脑的损害的潜在风险变得至关重要。