医护人员接种灭活 SARS-CoV-2 疫苗（科兴疫苗）的安全性和不良反应。

Safety and Adverse Effects of Inactive SARS-Cov-2 Vaccine (CoronaVac) in Health Care Professionals.

机构信息

Department of Family Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.

Department of Surgical Nursing, Tekirdag Namik Kemal University, School of Health, Tekirdag, Turkey.

出版信息

J Pak Med Assoc. 2022 Sep;72(9):1792-1796. doi: 10.47391/JPMA.4844.

DOI:10.47391/JPMA.4844

PMID:36280978

Abstract

OBJECTIVE

To assess adverse effects post-vaccination in healthcare professionals in the first vaccinated group against coronavirus disease-2019.

METHODS

The retrospective study was conducted at the Indus Hospital, Badin, The prospective study was conducted at the vaccination unit of a university hospital in Tekirdag, Turkey, from January to February 2021, and comprised healthcare professionals who came for receiving the second dose of the coronavirus disease-2019 inactivated severe acute respiratory syndrome coronavirus 2 vaccine 28 days after the first dose. Data was analysed using SPSS 18.

RESULTS

Of the 1088 subjects, 714(65.6%) were female with mean age 29.85±9.2 years and 374(34.4%) were male with mean age 29.57±9.85 years. Overall, local pain in the vaccinated area 495(45.5%), fatigue 266(24.4%), headache 261(23.9%) and muscle pain 197(18.1%) were very common adverse effects.

CONCLUSIONS

Inactivated severe acute respiratory syndrome coronavirus 2 vaccine was found to be safe.

摘要

目的

评估首组接种 2019 年冠状病毒病疫苗的医护人员的接种后不良反应。

方法

本回顾性研究于 2021 年 1 月至 2 月在巴基斯坦信德省巴丁的因迪斯医院进行，前瞻性研究在土耳其特克迪尔达格的一所大学医院的接种单位进行，纳入对象为首剂接种 28 天后前来接种 2019 年冠状病毒病灭活严重急性呼吸综合征冠状病毒 2 疫苗第二剂的医护人员。数据使用 SPSS 18 进行分析。

结果

1088 名受试者中，714 名（65.6%）为女性，平均年龄 29.85±9.2 岁，374 名（34.4%）为男性，平均年龄 29.57±9.85 岁。总体而言，接种部位局部疼痛 495 例（45.5%）、疲劳 266 例（24.4%）、头痛 261 例（23.9%）和肌肉疼痛 197 例（18.1%）是非常常见的不良反应。