难治性三叉神经痛行三叉神经阻滞术后的生活质量：回顾性队列研究及文献复习。
Quality of life after trigeminal nerve block in refractory trigeminal neuralgia: A retrospective cohort study and literature review.
机构信息
Department of Anaesthesiology and Intensive Care Medicine, Limoges University Hospital, Limoges, France.
Centre d'Epidémiologie, de Biostatistique et de Méthodologie de la Recherche (CEBIMER), Limoges, France.
出版信息
J Int Med Res. 2022 Oct;50(10):3000605221132027. doi: 10.1177/03000605221132027.
OBJECTIVE
To evaluate the effect of trigeminal nerve block (TNB) on patients' quality of life (QOL) 15 days after the procedure in patients with refractory TN.
METHODS
This retrospective observational cohort study involved patients receiving TNB (levobupivacaine, clonidine, corticosteroid) between 2014 and 2018 at a postoperative pain clinic in France. Change in QOL from Day 0 (before block) to Day 15 was assessed according to SF-12.
RESULTS
21 patients (62 ± 14 y) were included in the study. Most patients (71%) were referred following surgery or dentistry. Of the 9 patients (43%) who exhibited >10% increase in SF-12 scores and so were deemed responders, SF12-physical and SF12-mental were increased by mean differences of 17 and 9 points, respectively. The mean duration of block lasted 15 ± 59 days (range 1 to 90 days) and no severe adverse effects were observed.
CONCLUSION
Improved QOL was observed in approximately 50% of patients with trigeminal neuralgia (TN) two weeks after specific nerve block. The technique was easy to administer and well accepted by the patients.
目的
评估三叉神经阻滞（TNB）对难治性三叉神经痛患者术后 15 天生活质量（QOL）的影响。
方法
本回顾性观察性队列研究纳入了 2014 年至 2018 年期间在法国一家术后疼痛诊所接受 TNB（左旋布比卡因、可乐定、皮质类固醇）治疗的患者。根据 SF-12 评估 QOL 从第 0 天（阻滞前）到第 15 天的变化。
结果
21 名患者（62±14 岁）纳入研究。大多数患者（71%）是在手术后或牙科手术后转诊的。9 名（43%）患者的 SF-12 评分增加超过 10%，被认为是有反应者，SF12-身体和 SF12-心理评分分别增加了 17 和 9 分。阻滞的平均持续时间为 15±59 天（范围 1 至 90 天），未观察到严重不良事件。
结论
约 50%的三叉神经痛患者在特定神经阻滞两周后 QOL 得到改善。该技术易于实施，且患者易于接受。
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