Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Medicine (Baltimore). 2022 Oct 21;101(42):e31058. doi: 10.1097/MD.0000000000031058.
The COVID-19 pandemic reached the United States in early 2020 and spread rapidly across the country. This retrospective study describes the demographic and clinical characteristics of 308 children presenting to an Arkansas Children's emergency department (ED) or admitted to an Arkansas Children's hospital with COVID-19 in the first 10 months of the COVID-19 pandemic, prior to the emergence of clinically significant variants and available vaccinations. Adolescents aged 13 and older represented the largest proportion of this population. The most common presenting symptoms were fever, gastrointestinal symptoms, and upper respiratory symptoms. Patients with multisystem inflammatory syndrome in children (MIS-C) had a longer length of stay (LOS) than patients with acute COVID-19. Children from urban zip codes had lower odds of admission but were more likely to be readmitted after discharge. Nearly twenty percent of the study population incidentally tested positive for COVID-19. Despite lower mortality in children with COVID than in adults, morbidity and resource utilization are significant. With many Arkansas children living in rural areas and therefore far from pediatric hospitals, community hospitals should be prepared to evaluate children presenting with COVID-19 and to determine which children warrant transport to pediatric-specific facilities.
2020 年初,COVID-19 疫情蔓延至美国,并迅速在全美范围内传播。本回顾性研究描述了在 COVID-19 大流行的前 10 个月期间,308 名因 COVID-19 就诊于阿肯色儿童医院急诊部或住院的儿童的人口统计学和临床特征,此时尚未出现具有临床意义的变异株和可用疫苗。在该人群中,年龄在 13 岁及以上的青少年占比最大。最常见的首发症状是发热、胃肠道症状和上呼吸道症状。患有儿童多系统炎症综合征(MIS-C)的患者比患有急性 COVID-19 的患者的住院时间(LOS)更长。来自城市邮政编码的儿童住院的可能性较低,但出院后再次入院的可能性更高。研究人群中有近 20%的患者偶然检测出 COVID-19 阳性。尽管 COVID-19 患儿的死亡率低于成人,但发病率和资源利用仍很显著。由于许多阿肯色州的儿童居住在农村地区,远离儿科医院,因此社区医院应准备好评估出现 COVID-19 症状的儿童,并确定哪些儿童需要转运至儿科特定医疗机构。