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一名患有脊柱结核性脊柱炎的破伤风患者因全身痉挛引发的罕见脊柱骨折

A Rarely Occurring Spinal Fracture Precipitated by Generalized Spasms of Tetanus Patient with Spondylitis Tuberculosis.

作者信息

Huda Fathul, Ong Paulus Anam, Wibisono Yusuf, Dian Sofiati, Ganiem Ahmad Rizal

机构信息

Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia.

Department of Neurology, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin Central General Hospital, Bandung, West Java, Indonesia.

出版信息

Int Med Case Rep J. 2022 Oct 18;15:599-603. doi: 10.2147/IMCRJ.S367615. eCollection 2022.

Abstract

BACKGROUND

The occurrence of spinal fracture due to tetanus nowadays is extremely rare, as compared to the 1950s, since the widely available anti-tetanus and antispasmodic therapy. The spinal fracture in tetanus patients is usually reported in higher thoracic vertebrae, previously with a rate as high as 57.5%. Spondylitis is the most common form of skeletal tuberculosis (TB) and can cause a spinal fracture. In Indonesia, tetanus is still reported, while tuberculosis is still endemic; however, co-infection of both diseases is rarely reported.

CASE PRESENTATION

A 36-year-old male was brought to our hospital with jaw stiffness, accompanied by fever. A history of dental cavities was present, and 5 days prior, he experienced a fishing hook wound on his right index finger. There was no history of TB. Physical examination showed meningismus, 2 cm trismus, abdominal spasm, opisthotonus, and spontaneous muscle spasms, without dysautonomia. In the third week of hospitalization, while his tetanus condition improved, he complained of weakness in both legs. A thorough history taking revealed a history of backache for 3 years. A wedge-shaped fracture on his 11th and 12th thoracic vertebrae was observed on radiographic examination. A spinal TB diagnosis was made, and treatment was started. He refused to get spinal surgery, then went home with 4 out of 5 motor strength scale. After three months, he returned to his routine activity as a food hawker with no motor deficits.

CONCLUSION

Tetanus spinal fracture is extremely rare nowadays; a thorough history of spinal problems/medication is compulsory for anticipation. This patient's spinal fracture was deemed due to a preexisting TB spinal infection that was precipitated by prolonged continuous tetanic spasm due to general tetanus.

摘要

背景

与20世纪50年代相比,由于广泛使用抗破伤风和抗痉挛疗法,如今因破伤风导致的脊柱骨折极为罕见。破伤风患者的脊柱骨折通常发生在较高的胸椎,此前报道的发生率高达57.5%。脊柱炎是骨结核(TB)最常见的形式,可导致脊柱骨折。在印度尼西亚,仍有破伤风病例报告,而结核病仍然流行;然而,这两种疾病的合并感染很少被报道。

病例介绍

一名36岁男性因牙关紧闭并伴有发热被送至我院。有龋齿病史,5天前右手食指被鱼钩划伤。无结核病病史。体格检查显示有颈强直、2厘米牙关紧闭、腹部痉挛、角弓反张和自发性肌肉痉挛,无自主神经功能障碍。住院第三周,在破伤风病情好转时,他抱怨双腿无力。详细询问病史发现有3年背痛史。影像学检查发现第11和12胸椎有楔形骨折。诊断为脊柱结核并开始治疗。他拒绝接受脊柱手术,然后以5级肌力量表中的4级肌力回家。三个月后,他恢复了食品小贩的日常活动,无运动功能障碍。

结论

如今破伤风脊柱骨折极为罕见;为了做好预判,必须详细询问脊柱问题/用药史。该患者的脊柱骨折被认为是由于先前存在的脊柱结核感染,因全身性破伤风导致的长时间持续性破伤风痉挛而引发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d50/9587697/52339a69a40e/IMCRJ-15-599-g0001.jpg

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本文引用的文献

1
Functional Outcomes in Spinal Tuberculosis: A Review of the Literature.
Asian Spine J. 2021 Jun;15(3):381-391. doi: 10.31616/asj.2020.0086. Epub 2020 Sep 22.
2
Current Concepts in the Management of Vertebral Compression Fractures.
Curr Pain Headache Rep. 2020 Mar 20;24(5):16. doi: 10.1007/s11916-020-00849-9.
3
Spinal Tuberculosis: Current Concepts.
Global Spine J. 2018 Dec;8(4 Suppl):96S-108S. doi: 10.1177/2192568218769053. Epub 2018 Dec 13.
4
Vertebral compression fractures.
Br J Hosp Med (Lond). 2018 Jan 2;79(1):36-40. doi: 10.12968/hmed.2018.79.1.36.
5
An overview of clinical guidelines for the management of vertebral compression fracture: a systematic review.
Spine J. 2017 Dec;17(12):1932-1938. doi: 10.1016/j.spinee.2017.07.174. Epub 2017 Jul 21.
6
Diagnosis and Management of Vertebral Compression Fractures.
Am Fam Physician. 2016 Jul 1;94(1):44-50.
8
Bracing for thoracolumbar fractures.
Neurosurg Focus. 2014;37(1):E3. doi: 10.3171/2014.4.FOCUS1477.
9
Historical aspects of Pott's disease (spinal tuberculosis) management.
Eur Spine J. 2013 Jun;22 Suppl 4(Suppl 4):529-38. doi: 10.1007/s00586-012-2388-7. Epub 2012 Jul 17.
10
Spinal tuberculosis: a review.
J Spinal Cord Med. 2011;34(5):440-54. doi: 10.1179/2045772311Y.0000000023.

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