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未接种疫苗的成年人发生全身性破伤风。

Generalised tetanus in an unvaccinated adult.

机构信息

Department of Infectious Diseases, University College Galway, Newcastle, Galway, Ireland.

出版信息

Ir J Med Sci. 2010 Mar;179(1):135-6. doi: 10.1007/s11845-009-0305-9. Epub 2009 Mar 4.

DOI:10.1007/s11845-009-0305-9
PMID:19259759
Abstract

A 76-year-old previously well farmer presented having caught his left index finger in a gate. He gave no history of prior tetanus vaccination. The patient was treated in the emergency department; the wound cleaned, sutured and he was given tetanus toxoid prior to discharge. Eleven days later he represented unable to open his mouth. On examination he was noted to have trismus, generalised muscle spasms, diaphoresis and emotional lability and he was diagnosed with generalised tetanus.

摘要

一位 76 岁既往体健的农民主诉其左手食指被大门夹伤。他没有破伤风疫苗接种史。患者在急诊科接受治疗,伤口清洗、缝合,并在出院前注射了破伤风类毒素。11 天后,他无法张口就诊。检查时发现他有牙关紧闭、全身肌肉痉挛、出汗和情绪不稳定,诊断为全身性破伤风。

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本文引用的文献

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Magnesium sulphate for treatment of severe tetanus: a randomised controlled trial.硫酸镁治疗重度破伤风:一项随机对照试验。
Lancet. 2006 Oct 21;368(9545):1436-43. doi: 10.1016/S0140-6736(06)69444-0.
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Summary of notifiable diseases--United States, 2003.2003年美国法定传染病汇总
MMWR Morb Mortal Wkly Rep. 2005 Apr 22;52(54):1-85.
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Treatment of tetanus: an open study to compare the efficacy of procaine penicillin and metronidazole.破伤风的治疗:一项比较普鲁卡因青霉素和甲硝唑疗效的开放性研究。
Br Med J (Clin Res Ed). 1985 Sep 7;291(6496):648-50. doi: 10.1136/bmj.291.6496.648.
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Serologic therapy of tetanus in the United States, 1965-1971.
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