Kirkegaard C, Møller S E, Bjørum N
Acta Psychiatr Scand. 1978 Nov;58(5):457-62. doi: 10.1111/j.1600-0447.1978.tb03576.x.
The combination of electroconvulsive treatment (ECT) and i.v. L-tryptophan (T) was compared with ECT and saline in double-blind study comprising 20 patients with endogenous depression. No significant difference was found with regard to the number of ECT given nor in the rate of reduction of depressive symptoms. Except for a slight decrease of plasma total tryptophan in the palcepo group, no difference were found in plasma total and free tryptophan nor in the concentration of total tryptophan in the cerebrospinal fluid.
在一项包含20名内源性抑郁症患者的双盲研究中，对电休克治疗（ECT）与静脉注射L-色氨酸（T）的联合治疗和ECT与生理盐水的治疗进行了比较。在给予ECT的次数或抑郁症状减轻率方面未发现显著差异。除安慰剂组血浆总色氨酸略有下降外，血浆总色氨酸和游离色氨酸以及脑脊液中总色氨酸浓度均未发现差异。
