Laboratory of Neurosciences, Metabolism and Behavior, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, 70910-900 Brasilia, DF, Brazil.
Department of Pharmacy, School of Health Sciences, University of Brasilia, 70910-900 Brasilia, DF, Brazil.
Behav Brain Res. 2023 Feb 13;438:114173. doi: 10.1016/j.bbr.2022.114173. Epub 2022 Oct 22.
Schizophrenic patients show perceptual deficits, which may be detected in visual illusion tasks. Previous studies found that chronic patients show increased sensitivity to Müller-Lyer illusion as the disorder progresses, although there are a few conflicting reports in the scientific literature. To address these issues, moderate and chronic schizophrenic patients were tested on the Brentano version of the Müller-Lyer illusion task. Their performance was compared to first-degree relatives and unrelated matched controls. Chronic patients showed increased susceptibility to the illusion. Performance on the visual illusion task was not correlated to the number of years since disease onset, medication or (Positive and Negative Syndrome Scale) PANSS scores. The lack of association between illusion sensitivity and PANSS score may reflect the absence of the perceptual dimension in this scale. Based on these results, we suggest that susceptibility to the Müller-Lyer illusion is associated with the stage of schizophrenia rather than disease length.
精神分裂症患者表现出感知缺陷，这些缺陷可以在视觉错觉任务中检测到。先前的研究发现，随着病情的发展，慢性精神分裂症患者对 Muller-Lyer 错觉的敏感性增加，尽管科学文献中有一些相互矛盾的报告。为了解决这些问题，中度和慢性精神分裂症患者接受了 Muller-Lyer 错觉任务的 Brentano 版本测试。他们的表现与一级亲属和无关联的匹配对照组进行了比较。慢性患者对幻觉的敏感性增加。视觉错觉任务的表现与疾病发病年限、药物或（阳性和阴性症状量表）PANSS 评分无关。幻觉敏感性与 PANSS 评分之间缺乏关联可能反映了该量表中不存在感知维度。基于这些结果，我们认为对 Muller-Lyer 错觉的敏感性与精神分裂症的阶段有关，而不是疾病的长度。
