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眼内投射假体装置导致人眼温度升高

Temperature Elevation in the Human Eye Due To Intraocular Projection Prosthesis Device.

作者信息

Gongal Dipika, Thakur Siddhant, Panse Ashay, Stark John A, Yu Charles Q, Foster Craig D

机构信息

Department of Civil and Materials Engineering, University of Illinois at Chicago, Chicago, IL 60607.

Surgical Planner II, Arthrex Inc., Naples, FL 34119.

出版信息

J Therm Sci Eng Appl. 2021 Dec;13(6). doi: 10.1115/1.4050237. Epub 2021 Apr 19.

Abstract

Corneal opacity is a leading cause of blindness worldwide. Corneal transplantation and keratoprosthesis can restore vision but have limitations due to the shortage of donor corneas and complications due to infection. A proposed alternative treatment using an intraocular projection prosthesis device can treat corneal disease. In this study, we perform a transient thermal analysis of the bionic eye model to determine the power the device can produce without elevating the eye tissue temperature above the 2°C limit imposed by the international standard for implantable devices. A 3D finite element model, including blood perfusion and natural convection fluid flow of the eye, was created. The device was placed 1.95 mm from the iris, which experienced less than 2°C rise in the tissue temperature at a maximum power dissipation of LED at 100 mW and microdisplay at 25 mW.

摘要

角膜混浊是全球失明的主要原因。角膜移植和人工角膜可以恢复视力,但由于供体角膜短缺以及感染引起的并发症而存在局限性。一种提议的使用眼内投影假体装置的替代治疗方法可以治疗角膜疾病。在本研究中,我们对仿生眼模型进行瞬态热分析,以确定该装置在不使眼组织温度升高到可植入装置国际标准规定的2°C限制以上的情况下能够产生的功率。创建了一个三维有限元模型,包括眼睛的血液灌注和自然对流流体流动。该装置放置在距离虹膜1.95毫米处,在LED最大功率耗散为100毫瓦、微型显示器为25毫瓦时,虹膜处的组织温度升高不到2°C。

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本文引用的文献

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THERMAL ANALYSIS OF INTRAOCULAR ELECTRONIC DISPLAY PROJECTOR VISUAL PROSTHESIS.眼内电子显示投影仪视觉假体的热分析
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Characterization of an Electronic Corneal Prosthesis System.电子角膜假体系统的特性分析。
Curr Eye Res. 2020 Aug;45(8):914-920. doi: 10.1080/02713683.2019.1708957. Epub 2020 Jan 3.
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Global Survey of Corneal Transplantation and Eye Banking.全球角膜移植与眼库调查
JAMA Ophthalmol. 2016 Feb;134(2):167-73. doi: 10.1001/jamaophthalmol.2015.4776.
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Thermal heating of a retinal prosthesis: thermal model and in-vitro study.视网膜假体的热加热:热模型与体外研究。
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