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A Novel t(5;7)(q31;q21)/CDK6::IL3 in Immature T-cell Acute Lymphoblastic Leukemia With IL3 Expression and Eosinophilia.

作者信息

Pierini Valentina, Bardelli Valentina, Giglio Fabio, Arniani Silvia, Matteucci Caterina, Pellanera Fabrizia, Quintini Martina, Crescenzi Barbara, Bruno Alessandro, Sabattini Elena, Falcinelli Emanuela, Ruggeri Loredana, Ronchi Paola, Ponzoni Maurilio, Ciceri Fabio, Mecucci Cristina, La Starza Roberta

机构信息

Center for Hemato-Oncology Research (CREO), Hematology and Bone Marrow Transplantation Unit, Department of Medicine and Surgery, University of Perugia, Italy.

Haematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

出版信息

Hemasphere. 2022 Oct 19;6(11):e795. doi: 10.1097/HS9.0000000000000795. eCollection 2022 Nov.

DOI:10.1097/HS9.0000000000000795
PMID:36285071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9584195/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c5/9584195/192b3f8d36c7/hs9-6-e795-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c5/9584195/f04f4d5a7663/hs9-6-e795-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c5/9584195/192b3f8d36c7/hs9-6-e795-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c5/9584195/f04f4d5a7663/hs9-6-e795-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c5/9584195/192b3f8d36c7/hs9-6-e795-g002.jpg

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International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.国际髓系肿瘤和急性白血病分类：整合形态学、临床和基因组数据。
Blood. 2022 Sep 15;140(11):1200-1228. doi: 10.1182/blood.2022015850.
2
T-Cell Acute Lymphoblastic Leukemia: Biomarkers and Their Clinical Usefulness.T 细胞急性淋巴细胞白血病：生物标志物及其临床应用价值。
Genes (Basel). 2021 Jul 23;12(8):1118. doi: 10.3390/genes12081118.
3
Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia.
设计一种综合荧光原位杂交分析方法，用于 T 细胞急性淋巴细胞白血病的遗传分类。
J Mol Diagn. 2020 May;22(5):629-639. doi: 10.1016/j.jmoldx.2020.02.004. Epub 2020 Mar 4.
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T-cell acute lymphoblastic leukemia displays autocrine production of Interleukin-7.T 细胞急性淋巴细胞白血病呈现白细胞介素-7 的自分泌产生。
Oncogene. 2019 Nov;38(48):7357-7365. doi: 10.1038/s41388-019-0921-4. Epub 2019 Aug 15.
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High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement.高PIM1表达是伴有JAK/STAT激活或t(6;7)(p21;q34)/TRB@-PIM1重排的T细胞急性淋巴细胞白血病的一个生物标志物。
Leukemia. 2018 Aug;32(8):1807-1810. doi: 10.1038/s41375-018-0031-2. Epub 2018 Feb 2.
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A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia.
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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.早期 T 细胞前体急性淋巴细胞白血病的遗传基础。
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