Adamson Paul C, Currier Judith S, Uslan Daniel Z, Garner Omai B
Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Open Forum Infect Dis. 2022 Oct 19;9(10):ofac462. doi: 10.1093/ofid/ofac462. eCollection 2022 Oct.
Surges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections among health care workers (HCWs) have led to critical staffing shortages. From January 4 to February 4, 2022, we implemented a return-to-work antigen testing program for HCWs, and 870 HCWs participated. Antigen test positivity was 60.5% for those ≤5 days from symptom onset or positive polymerase chain reaction (PCR), and 47.4% were positive at day 7. Antigen positivity was associated with receiving a booster vaccination and being ≤6 days from symptom onset or PCR test, but not age or a symptomatic infection. Rapid antigen testing can be a useful tool to guide return-to-work and isolation precautions for HCWs following infection.
医护人员中严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染激增导致了严重的人员短缺。2022年1月4日至2月4日,我们对医护人员实施了返岗抗原检测计划,870名医护人员参与其中。症状出现或聚合酶链反应(PCR)检测呈阳性后≤5天的人员抗原检测阳性率为60.5%,第7天为47.4%呈阳性。抗原阳性与接种加强疫苗以及症状出现或PCR检测后≤6天有关,但与年龄或无症状感染无关。快速抗原检测可以作为指导医护人员感染后返岗和隔离预防措施的有用工具。