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背根入髓区损伤:技术细节与长期结果

Dorsal root entry zone lesion: nuances of the technique and long-term results.

作者信息

Ferraresi Stefano, Basso Elisabetta, Maistrello Lorenzo, Scerrati Alba, Di Pasquale Piero

机构信息

Department of Neurosurgery, Ospedale Santa Maria della Misericordia, Rovigo, Italy.

出版信息

Neurosurg Focus Video. 2020 Oct 1;3(2):V13. doi: 10.3171/2020.7.FOCVID2031. eCollection 2020 Oct.

DOI:10.3171/2020.7.FOCVID2031
PMID:36285263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9542238/
Abstract

The treatment of deafferentation pain is a primary goal of a referral center for peripheral nerve surgery. DREZ is an important asset in the neurosurgeon's armamentarium. The surgical technique and long-term results are analyzed in two series, with or without intraoperative monitoring (IOM). DREZotomy is highly effective in lumbar root avulsive injuries but is ineffective in resolving pain due to spinal cord injuries. Cervical DREZotomy for cancer pain is not superior to intrathecal morphine. In brachial plexus avulsive injuries, the largest series shows a 74% success rate, but the efficacy of the procedure is lost over time. No relevant difference has been observed since the introduction of IOM. The video can be found here: https://youtu.be/uG_kkQj5m1U.

摘要

去传入神经痛的治疗是周围神经外科转诊中心的主要目标。脊髓背根入髓区(DREZ)手术是神经外科医生的重要手段。本文分析了两个系列手术(有或没有术中监测(IOM))的手术技术和长期结果。DREZ切开术对腰神经根撕脱伤非常有效,但对脊髓损伤引起的疼痛无效。用于癌症疼痛的颈椎DREZ切开术并不优于鞘内注射吗啡。在臂丛神经撕脱伤中,最大的系列研究显示成功率为74%,但随着时间的推移该手术的疗效会丧失。自引入IOM以来,未观察到相关差异。视频可在此处找到:https://youtu.be/uG_kkQj5m1U 。

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Neurosurg Rev. 2025 Jan 2;48(1):17. doi: 10.1007/s10143-024-03136-y.

本文引用的文献

1
Efficacy and factors determining the outcome of dorsal root entry zone lesioning procedure (DREZotomy) in the treatment of intractable pain syndrome.背根入髓区毁损术(DREZotomy)治疗顽固性疼痛综合征的疗效及决定其预后的因素。
Acta Neurochir (Wien). 2017 Dec;159(12):2431-2442. doi: 10.1007/s00701-017-3345-3. Epub 2017 Oct 9.
2
Intraoperative Neurophysiological Monitoring (Motor and Somatosensory Evoked Potentials) in Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion Pain.臂丛神经撕脱伤疼痛的背根入髓区毁损术中的神经生理监测(运动和体感诱发电位)
Stereotact Funct Neurosurg. 2017;95(5):330-340. doi: 10.1159/000479889. Epub 2017 Oct 6.
3
Correlation of preoperative MRI with the long-term outcomes of dorsal root entry zone lesioning for brachial plexus avulsion pain.
术前磁共振成像与臂丛神经撕脱伤疼痛的背根入髓区毁损术长期疗效的相关性
J Neurosurg. 2016 May;124(5):1470-8. doi: 10.3171/2015.2.JNS142572. Epub 2015 Sep 25.
4
Usefulness of screening tools in the evaluation of long-term effectiveness of DREZ lesioning in the treatment of neuropathic pain after brachial plexus injury.筛查工具在评估脊髓背根入髓区毁损术治疗臂丛神经损伤后神经性疼痛长期疗效中的作用
BMC Neurol. 2014 Dec 9;14:225. doi: 10.1186/s12883-014-0225-9.
5
DREZotomy in the treatment of cancer pain: a review.脊髓背根入髓区切开术治疗癌痛:综述
Stereotact Funct Neurosurg. 2012;90(6):356-60. doi: 10.1159/000341072. Epub 2012 Aug 23.
6
Long term follow-up results of dorsal root entry zone lesions for intractable pain after brachial plexus avulsion injuries.臂丛神经撕脱伤后顽固性疼痛的背根入髓区损伤长期随访结果
Acta Neurochir Suppl. 2006;99:73-5. doi: 10.1007/978-3-211-35205-2_14.
7
Microsurgical lesioning in the dorsal root entry zone for pain due to brachial plexus avulsion: a prospective series of 55 patients.臂丛神经撕脱伤所致疼痛的背根入髓区显微手术损伤:55例患者的前瞻性系列研究
J Neurosurg. 2005 Jun;102(6):1018-28. doi: 10.3171/jns.2005.102.6.1018.
8
Three-dimensional MR myelography of traumatic injuries of the brachial plexus.臂丛神经创伤性损伤的三维磁共振脊髓造影
AJNR Am J Neuroradiol. 1997 Oct;18(9):1733-42.
9
Ultrasonic DREZ-operations for treatment of pain due to brachial plexus avulsion.超声引导下脊髓背根入髓区手术治疗臂丛神经撕脱伤所致疼痛
Acta Neurochir (Wien). 1993;122(1-2):76-81. doi: 10.1007/BF01446990.
10
Dorsal root entry zone lesions for intractable pain after trauma to the conus medullaris and cauda equina.圆锥和马尾创伤后顽固性疼痛的背根入髓区损伤
J Neurosurg. 1995 Jan;82(1):28-34. doi: 10.3171/jns.1995.82.1.0028.