David A S
Psychol Med. 1987 Aug;17(3):621-30. doi: 10.1017/s0033291700025861.
Neuropsychological studies have shown that the integrity of the posterior corpus callosum is necessary for accurate colour naming in the left visual field (LVF) and colour matching across hemifields. Using this model, 22 schizophrenics, 14 depressive and 16 healthy matched controls were given a battery of tachistoscopic tests of colour perception. The schizophrenics made significantly more errors, in naming colours in the LVF compared to depressives, and in matching colours across fields compared to depressives and normals. There were no differences between groups for right visual (RVF) colour naming or matching within right and left visual fields. These findings support the hypothesis that trans-callosal transmission may be impaired in schizophrenia and are unlikely to be due to a specific disorder of colour perception, neuroleptic drugs or generally impaired performance. Those schizophrenics whose LVF naming errors exceeded RVF errors were more likely to have first rank symptoms and showed less cerebral atrophy but did not differ on other variables. The techniques described may be useful for further research into interhemispheric function in schizophrenia.
神经心理学研究表明，胼胝体后部的完整性对于左视野（LVF）中的准确颜色命名以及跨半视野的颜色匹配是必要的。使用该模型，对22名精神分裂症患者、14名抑郁症患者和16名健康匹配对照组进行了一系列颜色感知的速示测试。与抑郁症患者相比，精神分裂症患者在LVF颜色命名方面以及与抑郁症患者和正常人相比在跨视野颜色匹配方面犯的错误明显更多。在右视野（RVF）颜色命名或左右视野内的颜色匹配方面，各组之间没有差异。这些发现支持了这样的假设，即精神分裂症患者的胼胝体间传递可能受损，而且不太可能是由于特定的颜色感知障碍、抗精神病药物或普遍受损的表现所致。那些LVF命名错误超过RVF错误的精神分裂症患者更有可能出现一级症状，脑萎缩程度较轻，但在其他变量上没有差异。所描述的技术可能有助于进一步研究精神分裂症患者的半球间功能。
