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[电离辐射对蜗牛神经元功能状态的影响。磷脂组成和游离脂肪酸水平]

[Effect of ionizing radiation on the functional state of snail neurons. Phospholipid composition and levels of free fatty acids].

作者信息

Egorova E G, Dvoretskiĭ A I, Annenkova S V, Shainskaia A M, Aĭrapetian S N

出版信息

Radiobiologiia. 1987 Jul-Aug;27(4):539-42.

PMID:3628736
Abstract

A study was made of the effect of ionizing radiation on the phospholipid composition and the level of free fatty acids in nervous ganglia of edible snails (Helix pomatia). Ionizing radiation was shown to decrease the total content of phospholipids and to change certain fractions and accumulation of lysoforms. The increase in the free fatty acid content indicated an activation of endogenous phospholipase hydrolysis. Model experiments on treatment of nervous ganglia with phospholipase A2 demonstrated a similarity of radiation-induced changes in the phospholipid content.

摘要

研究了电离辐射对食用蜗牛(玛瑙螺)神经节中磷脂成分和游离脂肪酸水平的影响。结果表明,电离辐射会降低磷脂的总含量,并改变某些组分以及溶血形式的积累。游离脂肪酸含量的增加表明内源性磷脂酶水解被激活。用磷脂酶A2处理神经节的模型实验证明了辐射诱导的磷脂含量变化具有相似性。

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