[电离辐射对蜗牛神经元功能状态的影响。环核苷酸水平与膜蛋白磷酸化]
[Effect of ionizing radiation on the functional state of snail neurons. Cyclic nucleotide levels and phosphorylation of membrane proteins].
作者信息
Dvoretskiĭ A I, Egorova E G, Shainskaia A M, Azatian K V, Aĭrapetian S N
出版信息
Radiobiologiia. 1987 Jul-Aug;27(4):462-7.
A study was made of the effect of ionizing radiation, phospholipase A2, and low concentrations of mediators (for instance, acetylcholine and gamma-aminobutyric acid) on the content of cyclic nucleotides and phosphorylation of membrane proteins of Helix pomatia nervous ganglia. Ionizing radiation was shown to decrease considerably the levels of cAMP and cGMP which correlated with the diminution of membrane phosphorylation. Phospholipase A2 and low doses of mediators produced a modifying effect on the cyclic nucleotide content.
研究了电离辐射、磷脂酶A2和低浓度介质（如乙酰胆碱和γ-氨基丁酸）对苹果螺神经节中环状核苷酸含量和膜蛋白磷酸化的影响。结果表明，电离辐射可显著降低cAMP和cGMP的水平，这与膜磷酸化的减少相关。磷脂酶A2和低剂量介质对环状核苷酸含量产生调节作用。
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