Fomenko B S, Salimova F V
Radiobiologiia. 1987 Jul-Aug;27(4):542-4.
In experiments on rat thymocytes obtained 15 min, 2 h and 4 h after irradiation of animals with the dose of 10 Gy it was found that 15 min and 4 h following irradiation changes occurred in their membranes increasing the lifetime of the excited state of anilinonaphthalene sulfonate and hydrofobicity and viscosity of its microenvironment. The indicated parameters did not vary from the controls 2 h following irradiation. The analysis of the data obtained prompted a suggestion that the observed changes were associated with the structural rearrangements in the plasma membrane rather than with its destruction. Model experiments on irradiated thymocyte suspensions showed that there was a correlation between changes in the cell membrane and meabolic processes.
在用10 Gy剂量照射动物后15分钟、2小时和4小时获取大鼠胸腺细胞进行的实验中发现，照射后15分钟和4小时，其细胞膜发生了变化，增加了苯胺萘磺酸盐激发态的寿命及其微环境的疏水性和粘度。照射后2小时，这些指标与对照组没有差异。对所得数据的分析提示，观察到的变化与质膜的结构重排有关，而非与其破坏有关。对照射后的胸腺细胞悬液进行的模型实验表明，细胞膜变化与代谢过程之间存在相关性。
