Wilkes S R, Mansour A M, Green W R
Retina. 1987 Summer;7(2):94-101.
Light- and electron-microscopic studies of 43 eyes with retroretinal membranes are presented. Associated features were severe blunt or penetrating injury, total retinal detachment, surbretinal proteinaceous exudate, and concomitant presence of preretinal fibrocellular or fibrovascular proliferations. The retinal pigment epithelium was found to be the major cellular component in early (as soon as 1 week) and chronic retinal detachment cases. Isolated glial-derived membranes were less common and were found in cases with chronic retinal detachment. Macrophages and fibrocytes, along with the retinal pigment epithelium and glia, were detected in mixed membranes. Subretinal proteins are thought to influence migration and attachment of the retinal pigment epithelium, which in turn provides a template for proliferation of the various cell types described.
本文呈现了对43只患有视网膜后膜眼睛的光镜和电镜研究。相关特征包括严重钝挫伤或穿透伤、完全性视网膜脱离、视网膜下蛋白性渗出物，以及视网膜前纤维细胞或纤维血管增殖的同时存在。在早期（最早1周）和慢性视网膜脱离病例中，视网膜色素上皮被发现是主要细胞成分。孤立的胶质源性膜较少见，见于慢性视网膜脱离病例。在混合膜中检测到巨噬细胞、纤维细胞以及视网膜色素上皮和神经胶质细胞。视网膜下蛋白被认为会影响视网膜色素上皮的迁移和附着，进而为上述各种细胞类型的增殖提供模板。
