• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

波斯尼亚和黑塞哥维那斯普斯卡共和国在新冠疫情之前及期间基层医疗环境中的抗生素使用情况。

Consumption of Antibiotics in Primary Care Setting before and during COVID-19 Pandemic in Republic of Srpska, Bosnia and Herzegovina.

作者信息

Sokolović Dragana, Drakul Dragana, Joksimović Bojan, Lalović Nenad, Avram Nada, Milić Marija, Nogo-Živanović Dajana, Mijović Biljana

机构信息

Faculty of Medicine Foča, University of East Sarajevo, Studentska 5, 73300 Foča, Bosnia and Herzegovina.

Department of Surgery, University Hospital Foča, Studentska 5, 73300 Foča, Bosnia and Herzegovina.

出版信息

Antibiotics (Basel). 2022 Sep 28;11(10):1319. doi: 10.3390/antibiotics11101319.

DOI:10.3390/antibiotics11101319
PMID:36289977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9598767/
Abstract

The pandemic of COVID-19 has brought many changes in health care systems at all levels of health care. The increase in the number of cases of COVID-19 has led to overuse and misuse of antibiotics.The aim of this study was to compare the consumption of antibiotics for systemic use in outpatients in the Republic of Srpska (RS), before and during the first year of the COVID-19 pandemic, as well as the association between antibiotic consumption and the rate of incidence and mortality of COVID-19. The total consumption of the antibiotics for systemic use (J01) in outpatients in the Republic of Srpska during 2019 was 19.40 DDD/TID, with an increase to 30.80 DDD/TID in 2020.Significantly higher use of penicillin (10.58 ± 11.01 DDD/TID in 2019 vs. 17.10 ± 13.63 DDD/TID in 2020), cephalosporins (2.68 ± 1.90 DDD/TID in 2019 vs. 5.93 ± 2.77 DDD/TID in 2020) and macrolides (2.14 ± 2.22 DDD/TID in 2019 vs. 3.40 ± 3.44 DDD/TID in 2020) was observed during the pandemic period. It is necessary to improve the prescribing practice of antibiotics at the primary health care level, public awareness about rational use of antibiotics, as well as the current antibiotic stewardship programs and control their implementation.

摘要

新型冠状病毒肺炎（COVID-19）大流行给各级医疗保健系统带来了诸多变化。COVID-19病例数的增加导致了抗生素的过度使用和滥用。本研究的目的是比较COVID-19大流行第一年之前和期间，塞尔维亚共和国（RS）门诊患者全身用抗生素的消耗量，以及抗生素消耗量与COVID-19发病率和死亡率之间的关联。2019年塞尔维亚共和国门诊患者全身用抗生素（J01）的总消耗量为19.40限定日剂量/千人口日，2020年增至30.80限定日剂量/千人口日。在大流行期间，观察到青霉素（2019年为10.58±11.01限定日剂量/千人口日，2020年为17.10±13.63限定日剂量/千人口日）、头孢菌素（2019年为2.68±1.90限定日剂量/千人口日，2020年为5.93±2.77限定日剂量/千人口日）和大环内酯类药物（2019年为2.14±2.22限定日剂量/千人口日，2020年为3.40±3.44限定日剂量/千人口日）的使用量显著增加。有必要改善初级卫生保健层面抗生素的处方行为、提高公众对抗生素合理使用的认识，以及完善当前的抗生素管理计划并监督其实施情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/5000ad669988/antibiotics-11-01319-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/948c5d2fb6f4/antibiotics-11-01319-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/2ee4dec71a6f/antibiotics-11-01319-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/5000ad669988/antibiotics-11-01319-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/948c5d2fb6f4/antibiotics-11-01319-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/2ee4dec71a6f/antibiotics-11-01319-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53fe/9598767/5000ad669988/antibiotics-11-01319-g003.jpg

相似文献

1
Consumption of Antibiotics in Primary Care Setting before and during COVID-19 Pandemic in Republic of Srpska, Bosnia and Herzegovina.波斯尼亚和黑塞哥维那斯普斯卡共和国在新冠疫情之前及期间基层医疗环境中的抗生素使用情况。
Antibiotics (Basel). 2022 Sep 28;11(10):1319. doi: 10.3390/antibiotics11101319.
2
Antibiotic consumption and antimicrobial resistance in the SARS-CoV-2 pandemic: A single-center experience.2019冠状病毒病大流行期间的抗生素使用与抗菌药物耐药性：单中心经验
Front Pharmacol. 2023 Mar 15;14:1067973. doi: 10.3389/fphar.2023.1067973. eCollection 2023.
3
Eleven-Year Trends in Lipid-Modifying Medicines Utilisation and Expenditure in a Low-Income Country: A Study from the Republic of Srpska, Bosnia and Herzegovina.低收入国家调脂药物使用与支出的十一年趋势：来自波斯尼亚和黑塞哥维那斯普斯卡共和国的一项研究
Clinicoecon Outcomes Res. 2023 Jun 29;15:513-523. doi: 10.2147/CEOR.S410711. eCollection 2023.
4
Trends in Antihypertensive Medicine Utilization in the Republic of Srpska, Bosnia and Herzegovina: An Eleven-Year Follow-Up.波斯尼亚和黑塞哥维那斯普斯卡共和国抗高血压药物使用趋势：十一年随访
Front Pharmacol. 2022 Jun 15;13:889047. doi: 10.3389/fphar.2022.889047. eCollection 2022.
5
Impact of over-the-counter restrictions on antibiotic consumption in Brazil and Mexico.非处方限制对巴西和墨西哥抗生素消费的影响。
PLoS One. 2013 Oct 16;8(10):e75550. doi: 10.1371/journal.pone.0075550. eCollection 2013.
6
Antibiotic Utilization during COVID-19: Are We Over-Prescribing?2019冠状病毒病期间的抗生素使用：我们是否存在过度处方的情况？
Antibiotics (Basel). 2023 Feb 2;12(2):308. doi: 10.3390/antibiotics12020308.
7
Hospital Antibiotic Consumption before and during the COVID-19 Pandemic in Hungary.匈牙利新冠疫情之前及期间的医院抗生素使用情况
Antibiotics (Basel). 2024 Jan 20;13(1):102. doi: 10.3390/antibiotics13010102.
8
[Surveillance of antibiotic resistance and antibiotic consumption in Medimurje].[梅迪穆尔耶地区抗生素耐药性与抗生素消费监测]
Acta Med Croatica. 2004;58(4):285-91.
9
Returned Rate and Changed Patterns of Systemic Antibiotic Use in Ambulatory Care in Hungary after the Pandemic-A Longitudinal Ecological Study.疫情后匈牙利门诊医疗中全身用抗生素的使用返回率及变化模式——一项纵向生态学研究
Antibiotics (Basel). 2024 Sep 5;13(9):848. doi: 10.3390/antibiotics13090848.
10
Hospital Antibiotic Use during COVID-19 Pandemic in Italy.意大利新冠疫情期间医院抗生素的使用情况。
Antibiotics (Basel). 2023 Jan 13;12(1):168. doi: 10.3390/antibiotics12010168.

引用本文的文献

1
A Retrospective Study of the Impact of the COVID-19 Pandemic on the Utilization and Quality of Antibiotic Use in a Tertiary Care Teaching Hospital in Low-Resource Settings.一项关于新冠疫情对资源匮乏地区三级护理教学医院抗生素使用情况及质量影响的回顾性研究
Antibiotics (Basel). 2025 May 23;14(6):535. doi: 10.3390/antibiotics14060535.
2
Public Knowledge, Attitudes, and Practices towards Antibiotic Use and Antimicrobial Resistance in Eastern Region of Bosnia and Herzegovina in the COVID-19 Pandemic.波斯尼亚和黑塞哥维那东部地区在新冠疫情期间对抗生素使用和抗菌药物耐药性的公众认知、态度及行为
Antibiotics (Basel). 2023 Aug 2;12(8):1274. doi: 10.3390/antibiotics12081274.
3

本文引用的文献

1
Update June 2022: management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline.更新于 2022 年 6 月：住院成人 2019 冠状病毒病（COVID-19）的管理：欧洲呼吸学会临床实践指南。
Eur Respir J. 2022 Aug 10;60(2). doi: 10.1183/13993003.00803-2022. Print 2022 Aug.
2
Outpatient Antibiotic Prescriptions in France: Patients and Providers Characteristics and Impact of the COVID-19 Pandemic.法国的门诊抗生素处方：患者和提供者特征以及新冠疫情的影响
Antibiotics (Basel). 2022 May 11;11(5):643. doi: 10.3390/antibiotics11050643.
3
MDR Pathogens Organisms as Risk Factor of Mortality in Secondary Pulmonary Bacterial Infections Among COVID-19 Patients: Observational Studies in Two Referral Hospitals in West Java, Indonesia.
Clinical Diagnostics of Bacterial Infections and Their Resistance to Antibiotics-Current State and Whole Genome Sequencing Implementation Perspectives.
细菌感染的临床诊断及其对抗生素的耐药性——现状与全基因组测序实施前景
Antibiotics (Basel). 2023 Apr 19;12(4):781. doi: 10.3390/antibiotics12040781.
4
Antibiotic consumption and antimicrobial resistance in the SARS-CoV-2 pandemic: A single-center experience.2019冠状病毒病大流行期间的抗生素使用与抗菌药物耐药性：单中心经验
Front Pharmacol. 2023 Mar 15;14:1067973. doi: 10.3389/fphar.2023.1067973. eCollection 2023.
多重耐药病原体作为新冠病毒感染患者继发性肺部细菌感染死亡率的风险因素：印度尼西亚西爪哇两家转诊医院的观察性研究
Int J Gen Med. 2022 May 6;15:4741-4751. doi: 10.2147/IJGM.S359959. eCollection 2022.
4
Consumption Trends of Antibiotics in Brazil During the COVID-19 Pandemic.新冠疫情期间巴西抗生素的消费趋势
Front Pharmacol. 2022 Mar 21;13:844818. doi: 10.3389/fphar.2022.844818. eCollection 2022.
5
Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020.2020 年克罗地亚 COVID-19 大流行期间阿奇霉素的使用情况。
PLoS One. 2022 Feb 2;17(2):e0263437. doi: 10.1371/journal.pone.0263437. eCollection 2022.
6
Seroprevalence of SARS-CoV-2 antibodies and knowledge, attitude and practice toward COVID-19 in the Republic of Srpska-Bosnia & Herzegovina: A population-based study.塞族共和国（波黑）血清新型冠状病毒 2 抗体流行率以及对 COVID-19 的知识、态度和实践：一项基于人群的研究。
PLoS One. 2022 Jan 28;17(1):e0262738. doi: 10.1371/journal.pone.0262738. eCollection 2022.
7
Correlation between Previous Antibiotic Exposure and COVID-19 Severity. A Population-Based Cohort Study.既往抗生素暴露与新冠病毒病严重程度的相关性。一项基于人群的队列研究。
Antibiotics (Basel). 2021 Nov 8;10(11):1364. doi: 10.3390/antibiotics10111364.
8
Decrease in community antibiotic consumption during the COVID-19 pandemic, EU/EEA, 2020.COVID-19 大流行期间欧盟/欧洲经济区社区抗生素消耗量下降
Euro Surveill. 2021 Nov;26(46). doi: 10.2807/1560-7917.ES.2021.26.46.2101020.
9
The Impact of the COVID-19 Pandemic on Demand for Emergency Ambulances in Victoria, Australia.新冠疫情对澳大利亚维多利亚州紧急救护车需求的影响。
Prehosp Emerg Care. 2021 Jul 16:1-7. doi: 10.1080/10903127.2021.1944409.
10
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.在国际严重急性呼吸系统与传染病联盟-世界卫生组织合作中心英国队列研究中，对首次大流行浪潮期间因 COVID-19 住院的患者中的合并感染、继发感染和抗菌药物使用情况进行的一项多中心、前瞻性队列研究。
Lancet Microbe. 2021 Aug;2(8):e354-e365. doi: 10.1016/S2666-5247(21)00090-2. Epub 2021 Jun 2.