Department of Physics, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.
Department of Electro-Optical Engineering, National Taipei University of Technology, Taipei 106, Taiwan.
Biosensors (Basel). 2022 Oct 10;12(10):856. doi: 10.3390/bios12100856.
Herein, we present an electrocatalyst constructed by zinc oxide hexagonal prisms/phosphorus-doped carbon nitride wrinkles (ZnO HPs/P-CN) prepared via a facile sonochemical method towards the detection of nitrofurantoin (NF). The ZnO HPs/P-CN-sensing platform showed amplified response and low-peak potential compared with other electrodes. The exceptional electrochemical performance could be credited to ideal architecture, rapid electron/charge transfer, good conductivity, and abundant active sites in the ZnO HPs/P-CN composite. Resulting from these merits, the ZnO HPs/P-CN-modified electrode delivered rapid response (2 s), a low detection limit (2 nM), good linear range (0.01-111 µM), high sensitivity (4.62 µA µM cm), better selectivity, decent stability (±97.6%), and reproducibility towards electrochemical detection of NF. We further demonstrated the feasibility of the proposed ZnO HPs/P-CN sensor for detecting NF in samples of water and human urine. All the above features make our proposed ZnO HPs/P-CN sensor a most promising probe for detecting NF in natural samples.
在此，我们提出了一种通过简便的超声化学方法制备的氧化锌六方棱柱/磷掺杂碳氮褶皱（ZnO HPs/P-CN）电催化剂，用于检测硝基呋喃妥因（NF）。与其他电极相比，ZnO HPs/P-CN 传感平台表现出放大的响应和低峰电位。卓越的电化学性能可归因于 ZnO HPs/P-CN 复合材料中的理想结构、快速的电子/电荷转移、良好的导电性和丰富的活性位点。由于这些优点，ZnO HPs/P-CN 修饰电极对 NF 的电化学检测表现出快速响应（2 s）、低检测限（2 nM）、良好的线性范围（0.01-111 µM）、高灵敏度（4.62 µA µM cm）、良好的选择性、良好的稳定性（±97.6%）和重现性。我们进一步证明了所提出的 ZnO HPs/P-CN 传感器在水和人尿样品中检测 NF 的可行性。所有这些特征使我们提出的 ZnO HPs/P-CN 传感器成为检测天然样品中 NF 的最有前途的探针。
