Rusztowicz Monika, Chilicka Karolina, Szyguła Renata, Odrzywołek Wiktoria, Yanakieva Antoniya, Asanova Binnaz, Wilczyński Sławomir
Department of Health Sciences, Institute of Health Sciences, University of Opole, 45-040 Opole, Poland.
Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland.
J Clin Med. 2022 Oct 14;11(20):6079. doi: 10.3390/jcm11206079.
The synergy of cosmetic acids, with their keratolytic and antibacterial properties, with the mechanical exfoliation of the epidermis brings faster and better treatment results. The aim of the study was to compare the effects of using only pyruvic acid and the synergy of microdermabrasion and chemical exfoliation. In total, 14 women diagnosed with acne took part in the study. Two areas were marked on the participants' faces: the right side (microdermabrasion treatment and a preparation containing pyruvic acid 40%) and the left side (preparation containing pyruvic acid 40%) without mechanical exfoliation. A series of four treatments was performed at 2-week intervals. Skin parameters such as stratum corneum hydration and sebum secretion were measured. Before the treatments, all patients had moderate acne according to GAGS (Min: 19, Max: 22, Md: 20), and after the treatments, it decreased to mild acne according to GAGS (Min: 13, Max: 17, Md: 140). On the right side of the face, there was a statistically significant reduction in sebum secretion in all the examined areas of the face and increase in the hydration of the stratum corneum. On the left side of the face, the differences were also observed in the decrease of sebum value and increase of hydration level; however, they were smaller than on the right side. The use of microdermabrasion in combination with pyruvic acid led to better results in the case of increased hydration and reduction of sebum secretion than using only pyruvic acid treatment.
具有角质溶解和抗菌特性的美容酸与表皮的机械剥脱作用协同，能带来更快、更好的治疗效果。本研究的目的是比较仅使用丙酮酸以及微晶磨皮与化学剥脱协同作用的效果。共有14名被诊断为痤疮的女性参与了该研究。在参与者面部标记两个区域：右侧（微晶磨皮治疗并使用含40%丙酮酸的制剂）和左侧（使用含40%丙酮酸的制剂），左侧不进行机械剥脱。每隔两周进行一系列四次治疗。测量了角质层水合作用和皮脂分泌等皮肤参数。治疗前，根据GAGS标准所有患者均为中度痤疮（最小值：19，最大值：22，中位数：20），治疗后，根据GAGS标准降至轻度痤疮（最小值：13，最大值：17，中位数：14）。在面部右侧，面部所有检查区域的皮脂分泌均有统计学意义的减少，角质层水合作用增加。在面部左侧，在皮脂值降低和水合水平增加方面也观察到差异；然而，这些差异小于右侧。与仅使用丙酮酸治疗相比，微晶磨皮与丙酮酸联合使用在增加水合作用和减少皮脂分泌方面产生了更好的效果。
