Bejjani Antoine, Khairani Candrika D, Campia Umberto, Piazza Gregory
Thrombosis Research Group, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
J Clin Med. 2022 Oct 18;11(20):6129. doi: 10.3390/jcm11206129.
Pulmonary embolism (PE) continues to represent a significant health care burden and its incidence is steadily increasing worldwide. Constantly evolving therapeutic options and the rarity of randomized controlled trial data to drive clinical guidelines impose challenges on physicians caring for patients with PE. Recently, PE response teams have been developed and recommended to help address these issues by facilitating a consensus among local experts while advocating the management of acute PE according to each individual patient profile. In this review, we focus on the clinical challenges supporting the need for a PE response team, report the current evidence for their implementation, assess their impact on PE management and outcomes, and address unanswered questions and future directions.
肺栓塞(PE)仍然是一个重大的医疗负担,其发病率在全球范围内正稳步上升。不断发展的治疗选择以及用于推动临床指南制定的随机对照试验数据的稀缺性,给照顾PE患者的医生带来了挑战。最近,已经建立并推荐了PE反应小组,以通过促进当地专家之间的共识,同时倡导根据每个患者的具体情况管理急性PE,来帮助解决这些问题。在本综述中,我们重点关注支持PE反应小组必要性的临床挑战,报告其实施的现有证据,评估其对PE管理和结局的影响,并探讨未解决的问题和未来方向。