Histological examination of combined effects of chemotherapeutic agents and differently fractionated irradiations in transplanted solid Ehrlich carcinoma of mice. II. Observations after dibromodulcitol treatment.

Dibromodulcitol treatment induced histological damages in solid Ehrlich carcinoma which increased on the effect of parallelly applied local fractionated X-irradiation. Comparing the effect of differently fractionated irradiations of the same total dose combined with dibromodulcitol treatment it can be stated that daily applied low radiation fractions cause more severe histologically demonstrable damage than relatively higher ones given in three to four day intervals.