D'Alessandris Quintino Giorgio, Ricciotti Maria Adelaide, Palombi Davide, Agostini Ludovico, Mattogno Pier Paolo, Della Pepa Giuseppe Maria, Albanese Alessio, Chiesa Silvia, Dispenza Sabrina, Meloni Eleonora, Tummolo Anita Maria, Pallini Roberto, Barillaro Christian, Olivi Alessandro, Lauretti Liverana
Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Rome, Italy.
Department of Palliative Care and Continuity of Care, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Rome, Italy.
J Pers Med. 2022 Sep 23;12(10):1565. doi: 10.3390/jpm12101565.
The onco-functional balance in neuro-oncology requires maximizing tumor removal while rigorously preserving patients' neurological status. When postoperative worsening prevents the implementation of oncologic treatments, palliative care service offers an individualized path for symptom and psychosocial distress relief. Here, we report on a series of 25 patients operated on for malignant brain tumor who did not undergo adjuvant treatments after neurosurgery; they represented 3.9% of the whole institutional surgical series. These patients were significantly older and had a lower preoperative Karnofsky performance status than the whole cohort. Importantly, in 22 out of 25 (88%) cases, a surgical complication occurred, leading to clinical worsening in 21 patients. For the end of life, the majority of patients chose a hospice care facility (72%). While a careful selection of brain tumor patients candidate to neurosurgery is required, palliative care service provided invaluable help in coping with patients' and caregivers' needs.
神经肿瘤学中的肿瘤功能平衡要求在严格保留患者神经状态的同时，最大限度地切除肿瘤。当术后病情恶化妨碍了肿瘤治疗的实施时，姑息治疗服务为缓解症状和心理社会困扰提供了个性化途径。在此，我们报告了一组25例接受恶性脑肿瘤手术的患者，他们在神经外科手术后未接受辅助治疗；他们占整个机构手术系列的3.9%。这些患者年龄明显更大，术前卡氏功能状态低于整个队列。重要的是，25例中有22例（88%）发生了手术并发症，导致21例患者临床病情恶化。在生命末期，大多数患者选择了临终关怀机构（72%）。虽然需要仔细挑选适合神经外科手术的脑肿瘤患者，但姑息治疗服务在满足患者和护理人员需求方面提供了宝贵帮助。
