Eberbach M A, Wahl R L, Argenta L C, Froelich J, Niederhuber J E
Surgery. 1987 Sep;102(3):433-42.
Lymphoscintigraphy with technetium99m antimony sulfur colloid or technetium99m human serum albumin helped direct the surgical management of 24 patients who had melanomas of the head, neck, and upper thorax. Eighteen (75%) patients had documented lymphatic flow to other than a single adjacent predictable lymph nodal group. Nineteen patients underwent lymphadenectomy. Availability of the scan altered surgical management in nine patients (47%) who required resection of nodes in addition to resection of adjacent nodes. The discovery of metastatic disease in one patient was clearly attributable to lymphoscintigraphy. This demonstrates the unpredictable lymphatic anatomy of this region and suggests that preoperative lymphoscintigraphy may be useful in directing the surgical management of cutaneous melanomas in which lymph node dissection is planned.
用锝99m硫胶体锑或锝99m人血清白蛋白进行的淋巴闪烁造影有助于指导24例头颈部和上胸部黑色素瘤患者的手术治疗。18例（75%）患者记录显示淋巴流向并非单一相邻可预测的淋巴结群。19例患者接受了淋巴结切除术。扫描结果改变了9例（47%）患者的手术治疗方案，这些患者除了切除相邻淋巴结外还需要切除其他淋巴结。1例患者转移病灶的发现显然归因于淋巴闪烁造影。这表明该区域淋巴解剖结构不可预测，并提示术前淋巴闪烁造影可能有助于指导计划进行淋巴结清扫的皮肤黑色素瘤的手术治疗。
